{"id":"W3011600984","doi":"10.4049/jimmunol.1900240","title":"Neutrophil Extracellular Trap–Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Neutrophil extracellular traps; Colorectal cancer; Medicine; Cancer research; Colon carcinoma; Trap (plumbing); Extracellular; Carcinoma; Metastasis; Oncology; Internal medicine; Cancer; Biology; Inflammation; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009475844,0.0002479848,0.0002626409,0.0001720356,0.0001009535,0.000191245,0.0001359871,0.0001903153,0.0009013647],"category_scores_gemma":[0.00005533732,0.00006239405,0.0001323988,0.00008133561,0.0001131847,0.000107171,0.00009432733,0.000520125,0.0001365065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001754395,"about_ca_system_score_gemma":0.000242598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003799477,"about_ca_topic_score_gemma":0.001231175,"domain_scores_codex":[0.9999621,0.000006678684,0.000002136954,0.00000434601,0.00001178858,0.00001290391],"domain_scores_gemma":[0.9999827,0.000001930742,0.000004123545,0.000001192397,0.000002723707,0.000007221191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005241315,0.0002464454,0.0001724662,0.0001292522,0.00001218314,0.000103917,0.00001067829,0.0001805973,0.987169,0.0002185214,0.0002295464,0.01100316],"study_design_scores_gemma":[0.0003646032,0.006550205,0.006211061,0.00002858117,0.00008957313,0.0009839641,0.0000296378,0.002474254,0.9726616,0.0001309618,0.01046436,0.00001117783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984948,0.008022795,0.003296099,0.0004255372,0.00009992065,0.0001413865,0.0002199211,0.0001166328,0.002729757],"genre_scores_gemma":[0.9904136,0.003916429,0.002623714,0.0001236207,0.00002082366,0.0000564439,0.0002627881,0.000008278951,0.002574279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009013647,"threshold_uncertainty_score":0.003015399,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02614957452702369,"score_gpt":0.3024387214865499,"score_spread":0.2762891469595262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}