{"id":"W3011675906","doi":"10.1007/s40273-020-00896-5","title":"A Budget Impact Model of the Addition of Telotristat Ethyl Treatment to the Standard of Care in Patients with Uncontrolled Carcinoid Syndrome","year":2020,"lang":"en","type":"article","venue":"PharmacoEconomics","topic":"Neuroendocrine Tumor Research Advances","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"Advanced Accelerator Applications; EMD Serono; Ipsen; Pfizer","keywords":"Carcinoid syndrome; Medicine; Discontinuation; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005290078,0.0001369353,0.0004973385,0.00006969662,0.00001987775,0.000003579903,0.0001606122,0.000005618445,0.00004181635],"category_scores_gemma":[0.00005805783,0.00007190373,0.0001198346,0.0001538015,0.00006730279,0.00006234695,0.00005505715,0.0001205544,0.000001351364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002945703,"about_ca_system_score_gemma":0.0003313177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001244682,"about_ca_topic_score_gemma":0.0001146194,"domain_scores_codex":[0.9990285,0.00006487603,0.0003451605,0.0001725863,0.0002029862,0.000185915],"domain_scores_gemma":[0.9992214,0.0000843215,0.0001887629,0.0002306543,0.0001511985,0.0001237022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.08115881,0.0008670613,0.508141,0.0009245718,0.0008040621,0.00008839123,0.006002913,0.3812019,0.01355904,0.00003846168,0.001436881,0.005776855],"study_design_scores_gemma":[0.1272137,0.05224936,0.1724181,0.0004401424,0.001075292,0.00005971156,0.002709187,0.0503946,0.5908049,0.0001233564,0.001814621,0.0006969899],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944581,0.0001168029,0.0000122279,0.001614047,0.00002288609,0.001637509,0.002062012,0.000005602009,0.00007074541],"genre_scores_gemma":[0.9994887,0.00004889377,0.000117929,0.000219992,0.00001224678,0.00005279629,0.00002763774,0.00002023387,0.00001155796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5772459,"threshold_uncertainty_score":0.2932149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01470325428347007,"score_gpt":0.3123216801549693,"score_spread":0.2976184258714992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}