{"id":"W3011712978","doi":"10.18632/aging.102944","title":"Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition","year":2020,"lang":"en","type":"article","venue":"Aging","topic":"GDF15 and Related Biomarkers","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute on Aging; University of Auckland; Ellison Medical Foundation","keywords":"Skeletal muscle; Myofibril; Biology; Myocyte; Gene expression; Internal medicine; Mitochondrion; Mitochondrial DNA; Endocrinology; Messenger RNA; Antioxidant; Gene; Cell biology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001094913,0.0001026748,0.0002597581,0.00005688909,0.00005296152,0.000004200552,0.00007209997,0.00007982841,0.0000235738],"category_scores_gemma":[0.0000466949,0.00006660701,0.00007426891,0.0003235742,0.00007062416,0.0000532914,0.00004530884,0.0002008579,0.000001053146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005105859,"about_ca_system_score_gemma":0.00007304735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003181082,"about_ca_topic_score_gemma":0.00001002378,"domain_scores_codex":[0.9989851,0.0001208673,0.0002801914,0.0001723907,0.0002750517,0.0001663716],"domain_scores_gemma":[0.9994513,0.00006782368,0.0002048993,0.0001317518,0.00006487567,0.00007937237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002145114,0.00009429612,0.03121977,0.00009954229,0.00006322045,0.00001537291,0.002746204,0.0000263103,0.9647226,0.000001165812,0.000471541,0.0003254258],"study_design_scores_gemma":[0.009324435,0.000368277,0.5233824,0.002871334,0.0001925505,0.00001029112,0.001347485,0.003323911,0.4588884,0.00001379109,0.00009513524,0.0001820544],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995581,0.000102212,0.00005335438,0.003181302,0.00004941324,0.0003197791,0.000006239597,0.00002294013,0.0006837045],"genre_scores_gemma":[0.9987341,0.00001048862,0.0004334093,0.000721518,0.00004183676,0.000003781032,0.00002486309,0.00001531561,0.00001464325],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5058343,"threshold_uncertainty_score":0.2716155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01079557370176406,"score_gpt":0.2391544846695483,"score_spread":0.2283589109677842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}