{"id":"W3011747051","doi":"10.3389/fimmu.2020.00361","title":"Advances in Developing CAR T-Cell Therapy for HIV Cure","year":2020,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Antiretroviral therapy; Human immunodeficiency virus (HIV); Medicine; Cell therapy; Virology; Intensive care medicine; Biology; Cell; Viral load; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003535534,0.0004765381,0.002938637,0.0008474664,0.0000402961,0.00001387769,0.0005117619,0.0007244176,0.0001384489],"category_scores_gemma":[0.0001092109,0.0004146821,0.0004125102,0.0008234124,0.0001918892,0.00007555383,0.0001007897,0.001262822,0.00002862552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001256792,"about_ca_system_score_gemma":0.001295128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001492238,"about_ca_topic_score_gemma":0.00001288487,"domain_scores_codex":[0.9973205,0.000308777,0.0007816185,0.0006942996,0.0001817765,0.0007129862],"domain_scores_gemma":[0.9989465,0.0002289178,0.0002162548,0.0004801809,0.00006549087,0.00006267406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000453313,0.00006544379,0.0001537534,0.005606398,0.0001867869,0.0001012151,0.0001956943,2.511289e-7,0.00002720245,0.00007548061,0.004678705,0.9884558],"study_design_scores_gemma":[0.0029571,0.0003332222,0.000006076906,0.003760868,0.00006173813,0.00004230368,0.0002634153,0.00001031078,0.00003801467,0.0002002319,0.9919848,0.0003419348],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000007019562,0.9910581,0.001920728,0.0006602045,0.001484852,0.003121654,0.00002644709,0.00004343835,0.001677593],"genre_scores_gemma":[9.677321e-7,0.986553,0.009529131,0.0001631149,0.0002175711,0.0009032226,0.0002545209,0.000125633,0.002252812],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9881138,"threshold_uncertainty_score":0.9998305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0393279410448842,"score_gpt":0.3567973900772711,"score_spread":0.3174694490323869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}