{"id":"W3011747051","doi":"10.3389/fimmu.2020.00361","title":"Advances in Developing CAR T-Cell Therapy for HIV Cure","year":2020,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Antiretroviral therapy; Human immunodeficiency virus (HIV); Medicine; Cell therapy; Virology; Intensive care medicine; Biology; Cell; Viral load; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005383029,0.0006685408,0.0007903463,0.001285532,0.0002264808,0.0008378373,0.0006073337,0.001154728,0.004534005],"category_scores_gemma":[0.0004455814,0.0001893854,0.00049565,0.0008308958,0.0003647562,0.001290167,0.0005514083,0.002288449,0.002137104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004281383,"about_ca_system_score_gemma":0.000706205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005322843,"about_ca_topic_score_gemma":0.0008799889,"domain_scores_codex":[0.9998672,0.00002700379,0.00001315709,0.0000251565,0.00004756595,0.00001990274],"domain_scores_gemma":[0.9998449,0.00007892755,0.00001418068,0.000005036506,0.00003928955,0.00001764195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007576535,0.0001193626,0.0000980988,0.01095534,0.00005708916,0.0001899082,0.00006529214,0.0004612223,0.005311133,0.01041294,0.0317041,0.9405496],"study_design_scores_gemma":[0.00002292296,0.000142362,0.0001986618,0.001516424,0.00006206174,0.0005474717,0.0000333866,0.0001423647,0.001034114,0.002174795,0.9941131,0.00001234788],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002231057,0.9963444,0.0004479799,0.0005605824,0.0004218823,0.000009452933,0.00001785945,0.00001625448,0.001958448],"genre_scores_gemma":[0.00107258,0.9969828,0.0004587556,0.0003520424,0.0002172971,0.00001386492,0.0000262969,0.000002567043,0.0008738113],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004534005,"threshold_uncertainty_score":0.01516777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0393279410448842,"score_gpt":0.3567973900772711,"score_spread":0.3174694490323869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}