{"id":"W3011784154","doi":"10.2174/1381612826666200311130812","title":"Development of an Oral Amphotericin B Formulation as an Alternative Approach to Parenteral Amphotericin B Administration in the Treatment of Blood-Borne Fungal Infections","year":2020,"lang":"en","type":"article","venue":"Current Pharmaceutical Design","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Amphotericin B; Medicine; Intensive care medicine; Drug; Oral administration; Antifungal; Pharmacology; Dermatology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002726985,0.0003429923,0.0003004665,0.0003533838,0.0001907457,0.000532396,0.0003184139,0.0004099112,0.001475685],"category_scores_gemma":[0.0002204419,0.000177667,0.0003548478,0.0001479705,0.0002149732,0.0004383724,0.0002921818,0.001018471,0.0005478421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00015559,"about_ca_system_score_gemma":0.0003014722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005250201,"about_ca_topic_score_gemma":0.0008242829,"domain_scores_codex":[0.9998462,0.00003502821,0.0000100143,0.0000295854,0.00006317435,0.00001592412],"domain_scores_gemma":[0.9999405,0.000007855387,0.00001425314,0.000003036813,0.000014454,0.0000198423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000297186,0.0006524348,0.0002111903,0.0005880558,0.00002635749,0.0006260305,0.00009464483,0.0003251994,0.8954002,0.001154298,0.001028675,0.09959573],"study_design_scores_gemma":[0.0007241653,0.01819262,0.00370079,0.0003504688,0.0002164835,0.004548237,0.0002125768,0.004289075,0.8305072,0.0005476184,0.1366404,0.0000703387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8489848,0.07048455,0.04581614,0.003241909,0.002241272,0.001250172,0.0002823137,0.000354706,0.02734431],"genre_scores_gemma":[0.8577754,0.04480183,0.08187114,0.001180976,0.000353062,0.0003945901,0.0003108273,0.00008448247,0.01322763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001475685,"threshold_uncertainty_score":0.004936695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2141712609928511,"score_gpt":0.4307251545645158,"score_spread":0.2165538935716646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}