{"id":"W3011994487","doi":"10.1002/cam4.2980","title":"Required efficacy for novel therapies in BCG‐unresponsive non‐muscle invasive bladder cancer: Do current recommendations really reflect clinically meaningful outcomes?","year":2020,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; University of Toronto; Health Sciences Centre; University Health Network","funders":"","keywords":"Medicine; Bladder cancer; Cystectomy; Clinical trial; Randomized controlled trial; Placebo; Oncology; Cancer; Intensive care medicine; Internal medicine; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.1099608,0.0008788585,0.001825258,0.001087578,0.000437559,0.003298176,0.002090302,0.002710608,0.003065433],"category_scores_gemma":[0.3086668,0.0004404591,0.00272778,0.0008783528,0.001641452,0.002730728,0.001164388,0.003132312,0.0003809526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003693172,"about_ca_system_score_gemma":0.004623418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002606987,"about_ca_topic_score_gemma":0.001549596,"domain_scores_codex":[0.9136778,0.06940212,0.005101601,0.003203828,0.007505994,0.001108608],"domain_scores_gemma":[0.5133562,0.4449396,0.02098935,0.008913874,0.01034367,0.001457293],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.009669373,0.001058706,0.07028523,0.007325174,0.003760463,0.0002383112,0.0008757341,0.6787888,0.002394693,0.08608502,0.007099195,0.1324193],"study_design_scores_gemma":[0.004378689,0.007716277,0.05526217,0.005904767,0.003736675,0.0003179665,0.0007816586,0.7223604,0.007508978,0.1687087,0.0230166,0.0003070166],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.5969981,0.02291466,0.3049471,0.03015864,0.000864276,0.004163697,0.007132331,0.0005287513,0.03229243],"genre_scores_gemma":[0.9582116,0.0009890617,0.03711164,0.001719755,0.00006345192,0.001014949,0.0005473459,0.00002894995,0.000313332],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.8900392,"threshold_uncertainty_score":0.5815352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.140079397406782,"score_gpt":0.4397971947391429,"score_spread":0.2997177973323609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}