{"id":"W3011994487","doi":"10.1002/cam4.2980","title":"Required efficacy for novel therapies in BCG‐unresponsive non‐muscle invasive bladder cancer: Do current recommendations really reflect clinically meaningful outcomes?","year":2020,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; University of Toronto; Health Sciences Centre; University Health Network","funders":"","keywords":"Medicine; Bladder cancer; Cystectomy; Clinical trial; Randomized controlled trial; Placebo; Oncology; Cancer; Intensive care medicine; Internal medicine; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004538146,0.0005020007,0.001271326,0.0002208441,0.000151682,0.00002226674,0.0003047163,0.0001738556,0.001012124],"category_scores_gemma":[0.001742006,0.0003778743,0.0002518906,0.0007055542,0.000246558,0.0001500411,0.00007752982,0.0005351392,0.00001916722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000535407,"about_ca_system_score_gemma":0.001520507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006703053,"about_ca_topic_score_gemma":0.0006326437,"domain_scores_codex":[0.9966868,0.0001040034,0.001158327,0.0009174239,0.0005100453,0.000623365],"domain_scores_gemma":[0.9969662,0.001058847,0.0004196006,0.0005158398,0.0005095126,0.0005299345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01754194,0.002727008,0.115245,0.001248919,0.003732106,0.000127409,0.07546915,0.0001531787,0.04977084,0.0004638957,0.1490204,0.5845003],"study_design_scores_gemma":[0.1203088,0.01330456,0.4289187,0.008310963,0.003576627,0.00002190202,0.006636176,0.0004908928,0.003231593,0.0007017921,0.4126772,0.001820885],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.3735882,0.02910707,0.005075197,0.5684254,0.006555151,0.01081165,0.001515329,0.0004911473,0.004430893],"genre_scores_gemma":[0.9487072,0.01513898,0.001688997,0.02859008,0.002678269,0.002182876,0.0002901446,0.0001643039,0.0005592066],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5826793,"threshold_uncertainty_score":0.9999011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.140079397406782,"score_gpt":0.4397971947391429,"score_spread":0.2997177973323609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}