{"id":"W3011997396","doi":"10.1038/s41467-020-15068-4","title":"Perivascular localization of macrophages in the intestinal mucosa is regulated by Nr4a1 and the microbiome","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"International Microbiome Centre, University of Calgary; Alberta Innovates - Health Solutions; Canadian Institutes of Health Research; Uehara Memorial Foundation; Japan Society for the Promotion of Science; Canada Research Chairs; Government of Canada; National Heart, Lung, and Blood Institute; Cumming School of Medicine, University of Calgary; Alberta Innovates; Heart and Stroke Foundation of Canada","keywords":"Lamina propria; Biology; Cell biology; Macrophage; Monocyte; Microbiome; CX3CR1; CCR2; Intestinal mucosa; Immunology; Pathology; Chemokine; Inflammation; Medicine; Epithelium; Chemokine receptor; Bioinformatics; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003460624,0.00007240342,0.0001277062,0.00003967903,0.0002650898,0.00003026833,0.0005844526,0.000116803,0.0000155338],"category_scores_gemma":[0.0001803062,0.00004656791,0.00004117452,0.0004978015,0.0003591634,0.00004721281,0.0000921922,0.0006027149,0.000002728053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001790736,"about_ca_system_score_gemma":0.00001317187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007736238,"about_ca_topic_score_gemma":0.00005600714,"domain_scores_codex":[0.999016,0.0004630734,0.0002234013,0.0001002875,0.0001054921,0.00009177948],"domain_scores_gemma":[0.9988573,0.00027543,0.00009577429,0.0006407211,0.0001060228,0.00002480131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001624737,0.001176269,0.01107249,0.0007408004,0.0001568903,0.000003954553,0.1381599,0.00004776417,0.07471935,0.1049091,0.6567665,0.0106222],"study_design_scores_gemma":[0.008471352,0.0002578064,0.01630522,0.0004145841,0.0001973642,0.0001046701,0.006290837,0.05117166,0.01795973,0.00291464,0.8954535,0.0004586155],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.06748246,0.06296686,0.0007248714,0.8654588,0.0001152331,0.001354772,0.0001499448,0.00008739808,0.001659645],"genre_scores_gemma":[0.9799156,0.001016601,0.0008418337,0.0180466,0.00001637845,0.000013122,0.000135979,0.000008012751,0.000005827182],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9124332,"threshold_uncertainty_score":0.261853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01561879105613666,"score_gpt":0.2943564337832522,"score_spread":0.2787376427271155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}