{"id":"W3011997396","doi":"10.1038/s41467-020-15068-4","title":"Perivascular localization of macrophages in the intestinal mucosa is regulated by Nr4a1 and the microbiome","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"International Microbiome Centre, University of Calgary; Alberta Innovates - Health Solutions; Canadian Institutes of Health Research; Uehara Memorial Foundation; Japan Society for the Promotion of Science; Canada Research Chairs; Government of Canada; National Heart, Lung, and Blood Institute; Cumming School of Medicine, University of Calgary; Alberta Innovates; Heart and Stroke Foundation of Canada","keywords":"Lamina propria; Biology; Cell biology; Macrophage; Monocyte; Microbiome; CX3CR1; CCR2; Intestinal mucosa; Immunology; Pathology; Chemokine; Inflammation; Medicine; Epithelium; Chemokine receptor; Bioinformatics; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002569814,0.0001699303,0.0002203503,0.0002700939,0.0001886245,0.0003416753,0.0001708003,0.0002773429,0.001793239],"category_scores_gemma":[0.0002006604,0.0001651089,0.0001950655,0.0001078377,0.0003374406,0.0002205334,0.0002844078,0.0003274226,0.0003956067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002114232,"about_ca_system_score_gemma":0.0001745229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006492368,"about_ca_topic_score_gemma":0.0009175739,"domain_scores_codex":[0.9997178,0.00005516812,0.00001893478,0.00007478368,0.00005188564,0.00008144778],"domain_scores_gemma":[0.9997665,0.00001842751,0.00009934961,0.00001975989,0.00003792536,0.00005794415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002415476,0.00001127964,0.001236717,0.00004119949,0.000003024197,0.0001051572,0.00003916457,0.00001945252,0.9969714,0.0001041597,0.00003583368,0.001191185],"study_design_scores_gemma":[0.00004467523,0.0008164222,0.1795207,0.00007633703,0.00004628927,0.001861219,0.001025354,0.001342037,0.8084536,0.0004495224,0.006341388,0.00002245487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926239,0.002975287,0.002489054,0.0001361218,0.0000348872,0.00001257061,0.0002243524,0.00005857296,0.001445121],"genre_scores_gemma":[0.993483,0.0007513021,0.002366345,0.00005627355,0.00001447351,0.00003361811,0.0001342967,0.00001839561,0.003142239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001793239,"threshold_uncertainty_score":0.005998969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01561879105613666,"score_gpt":0.2943564337832522,"score_spread":0.2787376427271155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}