{"id":"W3012154104","doi":"10.1002/cbic.202000003","title":"Circular Nucleic Acids: Discovery, Functions and Applications","year":2020,"lang":"en","type":"review","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Nucleic acid; Nanodevice; Aptamer; Deoxyribozyme; Exonuclease; Rolling circle replication; Ribozyme; Computational biology; DNA; Biosensor; Nanotechnology; Nucleic acid structure; Polymerase; Combinatorial chemistry; RNA; Biology; Chemistry; Biochemistry; Genetics; Materials science; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000691478,0.000425665,0.0007686153,0.00006364322,0.0001302205,0.00008015579,0.0002442689,0.000471194,0.000001891102],"category_scores_gemma":[0.00004393853,0.0003696544,0.0004565921,0.00028515,0.0001758487,0.000004986388,0.0002604291,0.0002346398,0.00002262342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003282248,"about_ca_system_score_gemma":0.0001144953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001271469,"about_ca_topic_score_gemma":0.00000113743,"domain_scores_codex":[0.9984368,0.00003667624,0.0003476938,0.0008378122,0.0001110058,0.0002300073],"domain_scores_gemma":[0.9989402,0.0000122607,0.0002143663,0.0006435867,0.00005341048,0.0001361263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004860916,0.00006232251,0.00000221817,0.002709914,0.0004406137,0.00000495769,0.000003756369,3.575655e-8,0.01447975,0.00007045184,0.003525037,0.9786961],"study_design_scores_gemma":[0.00006495928,0.00004350943,2.696516e-7,0.0003620815,0.0006393232,0.0000621761,0.00001848261,6.847798e-7,0.03841293,0.0000265395,0.9599562,0.0004128549],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000027088,0.9945872,0.003629854,0.00004663172,0.00003122476,0.0004746512,0.00018705,0.00008002344,0.0009362326],"genre_scores_gemma":[0.0007720805,0.9938735,0.0006504286,0.00008549886,0.0006446257,0.0001742726,0.001666281,0.00007243821,0.002060824],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9782832,"threshold_uncertainty_score":0.9998755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645072276417103,"score_gpt":0.2910891571168844,"score_spread":0.2746384343527134,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}