{"id":"W3012154104","doi":"10.1002/cbic.202000003","title":"Circular Nucleic Acids: Discovery, Functions and Applications","year":2020,"lang":"en","type":"review","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Nucleic acid; Nanodevice; Aptamer; Deoxyribozyme; Exonuclease; Rolling circle replication; Ribozyme; Computational biology; DNA; Biosensor; Nanotechnology; Nucleic acid structure; Polymerase; Combinatorial chemistry; RNA; Biology; Chemistry; Biochemistry; Genetics; Materials science; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006670986,0.001124271,0.001018207,0.00250112,0.0004248328,0.001225434,0.000881269,0.001331749,0.003630444],"category_scores_gemma":[0.0006200966,0.0006063727,0.0004725811,0.002394068,0.0007267274,0.00187976,0.0009293606,0.002456747,0.003270738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00100325,"about_ca_system_score_gemma":0.001190649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009997716,"about_ca_topic_score_gemma":0.001443429,"domain_scores_codex":[0.9997389,0.00002964706,0.00002569628,0.00005000894,0.0001215165,0.00003420994],"domain_scores_gemma":[0.9997814,0.00008496775,0.00002652529,0.00001194142,0.00006623413,0.00002888553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004508007,0.00009700489,0.0001025229,0.009638255,0.00004472452,0.0002053619,0.00007074406,0.0007699018,0.006601609,0.01701663,0.03039145,0.9350167],"study_design_scores_gemma":[0.000005177015,0.0000519143,0.0001422497,0.000772838,0.00001462077,0.000409171,0.00001764265,0.00008577394,0.001166844,0.001697182,0.9956236,0.0000128097],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000236796,0.9950123,0.000541223,0.0002551615,0.0004235913,0.0000125601,0.00002842125,0.00001622082,0.003473588],"genre_scores_gemma":[0.0009836281,0.9959223,0.0005759282,0.0002294078,0.0001941411,0.00001745515,0.00005269174,0.000003376807,0.002020957],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003630444,"threshold_uncertainty_score":0.01214498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645072276417103,"score_gpt":0.2910891571168844,"score_spread":0.2746384343527134,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}