{"id":"W3012208294","doi":"10.1016/j.jaci.2020.02.024","title":"Nasal allergen challenge and environmental exposure chamber challenge: A randomized trial comparing clinical and biological responses to cat allergen","year":2020,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hamilton Health Sciences; Population Health Research Institute; McMaster University; Inflamax Research (Canada)","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Immune Tolerance Network; National Institute of Diabetes and Digestive and Kidney Diseases; Regeneron Pharmaceuticals","keywords":"Allergen; Medicine; Randomized controlled trial; Immunology; Allergy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002178848,0.0003256075,0.002221243,0.0001017756,0.0001361906,0.00002790393,0.0001179806,0.0006682603,0.0001623141],"category_scores_gemma":[0.002032683,0.0002348292,0.0004154689,0.00006233398,0.001001831,0.0001066644,0.0003011223,0.0008492374,0.00001035912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001720928,"about_ca_system_score_gemma":0.00009453158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007753995,"about_ca_topic_score_gemma":0.00002072082,"domain_scores_codex":[0.9950235,0.001502676,0.002338536,0.0005384875,0.0002600339,0.0003367275],"domain_scores_gemma":[0.9968466,0.001579979,0.0006242064,0.0001926927,0.00009804243,0.0006585051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9753686,0.001035026,0.005964699,0.00001401116,0.004400355,0.0006371217,0.001788958,0.000003926999,0.0002772876,0.0006230392,0.0004677946,0.009419217],"study_design_scores_gemma":[0.8301601,0.02938479,0.11578,0.0001395076,0.0003969181,0.001293662,0.00206663,0.001105464,0.000009769782,0.0003704517,0.01877181,0.0005209038],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9698872,0.009181225,0.0001550592,0.01925328,0.0006511615,0.0005905769,0.000003989296,0.00002275597,0.0002547777],"genre_scores_gemma":[0.8629148,0.1335766,0.0006088578,0.001712872,0.001057423,0.000007731657,0.00001275738,0.00002475116,0.00008418188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1452085,"threshold_uncertainty_score":0.9576058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08683887788263121,"score_gpt":0.3439577317672898,"score_spread":0.2571188538846586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}