{"id":"W3012220699","doi":"10.1101/2020.03.20.000968","title":"Glucose extends lifespan through enhanced intestinal barrier integrity in <i>Drosophila</i>","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Mechanism (biology); Biology; Drosophila (subgenus); Disease; Drosophila melanogaster; Cell biology; Endocrinology; Internal medicine; Medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001164856,0.0003028062,0.0001824059,0.0002733863,0.000171719,0.0002802075,0.0001892737,0.0002338625,0.001410169],"category_scores_gemma":[0.00006450947,0.0001206486,0.000227253,0.0001018822,0.0002530586,0.0001803584,0.000253328,0.0005560364,0.0002990855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003382766,"about_ca_system_score_gemma":0.0001526508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00114312,"about_ca_topic_score_gemma":0.002103416,"domain_scores_codex":[0.9999435,0.000007405151,0.000006123964,0.00001778512,0.0000141617,0.00001107851],"domain_scores_gemma":[0.9998846,0.00001322361,0.00004879772,0.00001047238,0.0000126745,0.00003033337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003611718,0.000005662478,0.0002935597,0.00003290687,0.000005642511,0.00003004858,0.000006090074,0.00003778527,0.998598,0.0001574673,0.00009081591,0.000705961],"study_design_scores_gemma":[0.00002412904,0.0001791237,0.02531732,0.00003212929,0.00005502178,0.0004887147,0.00005726246,0.001529826,0.9623814,0.0004138245,0.009503047,0.00001817767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861879,0.002369314,0.005094068,0.0004149408,0.00005150828,0.00002215724,0.002008993,0.0002157165,0.003635435],"genre_scores_gemma":[0.9871125,0.001426759,0.006056596,0.0002653732,0.00001741632,0.00002696168,0.001316636,0.0001171177,0.003660734],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001410169,"threshold_uncertainty_score":0.004717469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01757995898016495,"score_gpt":0.2387658724388266,"score_spread":0.2211859134586617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}