{"id":"W3012262711","doi":"10.1038/s41564-020-0687-z","title":"Structural coordination of polymerization and crosslinking by a SEDS–bPBP peptidoglycan synthase complex","year":2020,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":141,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; U.S. Department of Health and Human Services; Government of Canada; National Institutes of Health; Canadian Institutes of Health Research; Harvard Medical School; Howard Hughes Medical Institute","keywords":"Peptidoglycan; ATP synthase; Polymerization; Chemistry; Enzyme; Cell biology; Biochemistry; Biology; Organic chemistry; Polymer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003740847,0.0002717988,0.0002746206,0.000130324,0.000461748,0.0006295723,0.0004836697,0.000342329,0.002107604],"category_scores_gemma":[0.000427543,0.0003035459,0.0001624858,0.0001145272,0.0003881799,0.0004140234,0.0005173237,0.0007295047,0.0005232585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007681989,"about_ca_system_score_gemma":0.0003637733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008704267,"about_ca_topic_score_gemma":0.001157758,"domain_scores_codex":[0.9998148,0.00002195034,0.00001083674,0.00004988017,0.00005494532,0.00004758596],"domain_scores_gemma":[0.9996896,0.00005079939,0.00005467689,0.00002522077,0.00002751399,0.0001521353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002726609,0.0000585483,0.0006025869,0.00003345373,0.00001304386,0.0001898241,0.00008694236,0.0008222593,0.9950251,0.0009103413,0.0001821157,0.001803169],"study_design_scores_gemma":[0.00004315402,0.0001611497,0.005417949,0.000007968665,0.000008992684,0.0001869863,0.0001156488,0.01073498,0.9807598,0.0004454347,0.002094273,0.00002377078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963243,0.0002144253,0.002009674,0.0001149017,0.00002599448,0.000008914139,0.00003792237,0.00008184931,0.001182016],"genre_scores_gemma":[0.9980489,0.00005253071,0.0009024646,0.00002489781,0.000005892265,0.000005557041,0.00007639559,0.00002135813,0.0008619436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002107604,"threshold_uncertainty_score":0.007050574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00893969445260255,"score_gpt":0.2333411276452824,"score_spread":0.2244014331926799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}