{"id":"W3012305156","doi":"10.1002/cbin.11340","title":"Epidermal growth factor receptor (EGFR) involvement in epithelial‐derived cancers and its current antibody‐based immunotherapies","year":2020,"lang":"en","type":"review","venue":"Cell Biology International","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Cetuximab; Epidermal growth factor receptor; Panitumumab; Cancer research; Gefitinib; Growth factor receptor; Receptor tyrosine kinase; KRAS; Colorectal cancer; Biology; Cancer; EGFR inhibitors; Lung cancer; Signal transduction; Tyrosine kinase; Medicine; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003163678,0.0005754689,0.0007707631,0.001582203,0.0001743344,0.0006071216,0.0005015112,0.0006220351,0.002829799],"category_scores_gemma":[0.0002935695,0.0001822188,0.000336869,0.001760579,0.0002712086,0.0007523918,0.0004261108,0.001283357,0.001564997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004228798,"about_ca_system_score_gemma":0.0006504373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007918363,"about_ca_topic_score_gemma":0.001491363,"domain_scores_codex":[0.9999068,0.00001352592,0.00001274402,0.00001769848,0.00003829648,0.00001101855],"domain_scores_gemma":[0.9999142,0.00003357562,0.00001378811,0.000003118353,0.00002466492,0.00001061565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007264454,0.00007496997,0.0001201259,0.01507424,0.00006579136,0.0001397952,0.0000473568,0.0003694799,0.002951442,0.003767745,0.02501911,0.9522973],"study_design_scores_gemma":[0.00001601352,0.00009635821,0.000594062,0.002165096,0.000105574,0.001130905,0.00003140857,0.00007964962,0.0007156717,0.001433917,0.99362,0.00001136421],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001418103,0.9984628,0.00008346064,0.0001449591,0.0001261167,0.000003417541,0.00001280423,0.000005916708,0.001018709],"genre_scores_gemma":[0.0006416184,0.9984182,0.0000950626,0.0001251404,0.00008679206,0.000004438592,0.00002221511,9.015224e-7,0.0006056731],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002829799,"threshold_uncertainty_score":0.009466588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04392795639133396,"score_gpt":0.3861711967582503,"score_spread":0.3422432403669163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}