{"id":"W3012330436","doi":"10.1016/j.gene.2020.144593","title":"Genomic landscape of transcriptionally active histone arginine methylation marks, H3R2me2s and H4R3me2a, relative to nucleosome depleted regions","year":2020,"lang":"en","type":"article","venue":"Gene","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Histone; Chromatin; Histone H4; Histone methyltransferase; Nucleosome; Histone code; Acetylation; Histone methylation; Methylation; EZH2; Genetics; Molecular biology; DNA methylation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005717285,0.0001340921,0.0001720729,0.00006101079,0.00005207577,0.000006156542,0.0000796786,0.000141103,0.00004366363],"category_scores_gemma":[0.00005098484,0.0001481855,0.00006796523,0.0001736797,0.00004838826,0.000008453518,0.00004431722,0.00007755253,0.000006464666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003201417,"about_ca_system_score_gemma":0.00006821905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001284733,"about_ca_topic_score_gemma":0.00003655387,"domain_scores_codex":[0.9991215,0.00005354944,0.0002232948,0.0003479057,0.0001165554,0.0001371939],"domain_scores_gemma":[0.999483,0.00001284519,0.0001114137,0.0001656339,0.0001040442,0.0001230367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004486888,0.00001701519,0.0001890006,0.00001164525,0.0001137334,6.845106e-7,0.0005259876,0.001151933,0.9942206,0.0001495467,0.001235378,0.001935779],"study_design_scores_gemma":[0.002155412,0.0009018202,0.1033227,0.00002148329,0.0001736535,0.00001874661,0.0001585674,0.001610246,0.8494865,0.0004224468,0.04128145,0.0004469036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793577,0.001721986,0.01493473,0.002985198,0.00007749937,0.0003262356,0.00008914029,0.00001678865,0.0004906897],"genre_scores_gemma":[0.9960286,0.000202601,0.002544644,0.0002921565,0.0001927,0.0000179086,0.000399712,0.00002720677,0.0002944533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1447341,"threshold_uncertainty_score":0.6042829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01179357390594254,"score_gpt":0.2384429392089154,"score_spread":0.2266493653029729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}