{"id":"W3012330436","doi":"10.1016/j.gene.2020.144593","title":"Genomic landscape of transcriptionally active histone arginine methylation marks, H3R2me2s and H4R3me2a, relative to nucleosome depleted regions","year":2020,"lang":"en","type":"article","venue":"Gene","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Histone; Chromatin; Histone H4; Histone methyltransferase; Nucleosome; Histone code; Acetylation; Histone methylation; Methylation; EZH2; Genetics; Molecular biology; DNA methylation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007818943,0.00008594269,0.0001637571,0.0005153157,0.0002229212,0.0003814724,0.0001674208,0.0001911734,0.006539928],"category_scores_gemma":[0.0001937156,0.0001230984,0.00013798,0.0002942701,0.000206836,0.0001202593,0.000173659,0.0002864065,0.0004719208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002018454,"about_ca_system_score_gemma":0.0001396747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002253395,"about_ca_topic_score_gemma":0.003446355,"domain_scores_codex":[0.9999018,0.000009784827,0.000003001887,0.00004715432,0.00001450744,0.00002376239],"domain_scores_gemma":[0.999797,0.00006156199,0.00003931297,0.00001526975,0.00002492988,0.00006191992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001013943,0.00001800413,0.009145801,0.00004085929,0.00005251593,0.00008876625,0.00008563443,0.00024588,0.9844721,0.0006236273,0.0001899955,0.004022978],"study_design_scores_gemma":[0.00006245275,0.000476046,0.7231181,0.00001018451,0.000156845,0.001222204,0.000460532,0.003384146,0.2646283,0.001125301,0.005330354,0.00002560071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954359,0.0006132421,0.001057148,0.00007248292,0.000007523117,0.000002527119,0.001161677,0.00007074465,0.001578898],"genre_scores_gemma":[0.9967555,0.00009167089,0.000406842,0.00003014774,0.000005209959,0.000003865562,0.0006759794,0.00001326316,0.002017447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006539928,"threshold_uncertainty_score":0.0218783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01179357390594254,"score_gpt":0.2384429392089154,"score_spread":0.2266493653029729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}