{"id":"W3012335496","doi":"10.1101/2020.03.16.994293","title":"A CTGF-YAP regulatory pathway is essential for angiogenesis and barriergenesis in the retina","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Eye Institute; National Institutes of Health","keywords":"CTGF; Cell biology; Angiogenesis; Growth factor; Matricellular protein; Biology; Connective tissue; Extracellular matrix; Cancer research; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001082333,0.0005122674,0.0004593435,0.0001661064,0.0001758767,0.0001569406,0.0007706246,0.0006113717,0.00002590317],"category_scores_gemma":[0.0007800734,0.0004883729,0.0002548705,0.0003428286,0.0001944893,0.000008625197,0.0008070618,0.0003618463,0.000007098466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000917753,"about_ca_system_score_gemma":0.0006887582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005853472,"about_ca_topic_score_gemma":0.0000154472,"domain_scores_codex":[0.9967987,0.0003199533,0.0004242982,0.001398804,0.0004691396,0.000589108],"domain_scores_gemma":[0.9977233,0.00008052263,0.0002056675,0.001278263,0.0004722301,0.0002399873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001577481,0.00005544722,0.008731591,0.0003703065,0.0001586609,0.00002533762,0.00003844712,0.000003706238,0.9887084,0.000177345,0.00156385,0.00000916193],"study_design_scores_gemma":[0.0006202418,0.0001569718,0.1045159,0.0000807563,0.00007705863,5.576301e-8,0.00001528305,0.00009691365,0.8699335,0.000008451548,0.02387013,0.0006247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910173,0.004398633,0.0009420814,0.00115852,0.0002838906,0.001501859,0.0006443936,0.0000469611,0.000006388748],"genre_scores_gemma":[0.9967929,0.0003899179,0.0008165092,0.0004137402,0.0007340974,0.0007114392,0.000002689685,0.000131932,0.000006838009],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1187749,"threshold_uncertainty_score":0.9997568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01792718184854474,"score_gpt":0.2501481101544473,"score_spread":0.2322209283059025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}