{"id":"W3012353851","doi":"10.1073/pnas.1920017117","title":"Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress","year":2020,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Pancreatitis Pathology and Treatment","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; Government of Canada; Neuroendocrine Tumor Research Foundation","keywords":"MEN1; Pancreas; Proinflammatory cytokine; Biology; Cancer research; Inflammation; Endocrinology; Internal medicine; Endocrine system; Medicine; Immunology; Hormone","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003081867,0.0002722509,0.0002296043,0.0002819214,0.000195844,0.0005011862,0.0001458088,0.000173988,0.0009600953],"category_scores_gemma":[0.0001712584,0.0001243542,0.0002031275,0.0001263205,0.0002833439,0.0002585184,0.0002741309,0.0003722468,0.0002073409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003551651,"about_ca_system_score_gemma":0.0002833523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000216301,"about_ca_topic_score_gemma":0.0005886093,"domain_scores_codex":[0.9998589,0.00003160498,0.00001175587,0.00002607986,0.0000374839,0.00003420756],"domain_scores_gemma":[0.9998597,0.00001296921,0.00005054174,0.00001711442,0.0000107565,0.00004888384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003455025,0.00001615458,0.002191643,0.00005729427,0.00001406942,0.0001576706,0.00004231243,0.0001426462,0.9922987,0.000285401,0.00007538764,0.004373208],"study_design_scores_gemma":[0.00002934165,0.000520386,0.07650039,0.00002569096,0.00004421096,0.001202835,0.0001886968,0.00107951,0.9087139,0.0005216685,0.0111581,0.00001532782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893612,0.006091778,0.002277886,0.0002968574,0.00003786708,0.00001120528,0.0002059997,0.00008451904,0.001632642],"genre_scores_gemma":[0.9943012,0.002259303,0.0008909233,0.00005628424,0.00001298473,0.000009123692,0.0001808538,0.00001090693,0.002278346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009600953,"threshold_uncertainty_score":0.003211796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04105785960178764,"score_gpt":0.320607754468184,"score_spread":0.2795498948663963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}