{"id":"W3012531077","doi":"10.1038/s41467-020-15090-6","title":"UBB pseudogene 4 encodes functional ubiquitin variants","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Q & T Research; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Université de Sherbrooke","keywords":"Pseudogene; Biology; Gene; Genetics; Ubiquitin; Proteomics; Computational biology; Ubiquitins; Genome; Ubiquitin ligase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002426991,0.0009046411,0.0003282812,0.001292507,0.0004486159,0.0005512047,0.0004339058,0.0006232986,0.005036577],"category_scores_gemma":[0.0004229177,0.0003245791,0.0005987287,0.0008264651,0.00045963,0.0002671752,0.0003986409,0.0006131148,0.002693898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000631158,"about_ca_system_score_gemma":0.0004818242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008569211,"about_ca_topic_score_gemma":0.0008400817,"domain_scores_codex":[0.9996465,0.0000517023,0.00003305518,0.0001001014,0.0001218597,0.00004673734],"domain_scores_gemma":[0.9995003,0.0001033884,0.0001697446,0.00008109636,0.00005237573,0.00009307147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003487515,0.00003878163,0.001245911,0.00008589471,0.00002967423,0.0005794753,0.00001261795,0.0001766918,0.9945033,0.0004773241,0.0004226783,0.002079009],"study_design_scores_gemma":[0.00006811225,0.0002258201,0.02683231,0.00002826813,0.00007311944,0.004134524,0.00006178332,0.002502529,0.9274325,0.0009779383,0.03761456,0.00004852371],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9424766,0.003017816,0.0234061,0.000375194,0.0005409037,0.0001506331,0.0253833,0.001256518,0.003392983],"genre_scores_gemma":[0.9228559,0.001218783,0.01823836,0.0001951511,0.00005862348,0.0001466473,0.04297007,0.0003283273,0.01398808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005036577,"threshold_uncertainty_score":0.01684898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03970417134223923,"score_gpt":0.2816704604476527,"score_spread":0.2419662891054135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}