{"id":"W3012531077","doi":"10.1038/s41467-020-15090-6","title":"UBB pseudogene 4 encodes functional ubiquitin variants","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Q & T Research; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Université de Sherbrooke","keywords":"Pseudogene; Biology; Gene; Genetics; Ubiquitin; Proteomics; Computational biology; Ubiquitins; Genome; Ubiquitin ligase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001273922,0.0001186277,0.00009499774,0.00002124645,0.0002204013,0.0000261994,0.0007130231,0.0002928933,0.000118001],"category_scores_gemma":[0.0002700478,0.0001197353,0.0000802978,0.0001484569,0.00008895599,0.000004561665,0.0004360468,0.0004422019,0.00008477944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008278115,"about_ca_system_score_gemma":0.00009587377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003482065,"about_ca_topic_score_gemma":0.000031273,"domain_scores_codex":[0.9992188,0.000116673,0.0001554391,0.000237112,0.000117101,0.0001548584],"domain_scores_gemma":[0.9987458,0.0000331365,0.00006255027,0.0009161123,0.0001242913,0.000118116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006053568,0.00009906889,0.001596014,0.0000122836,0.00007170688,0.000001160103,0.0001242774,0.0000210703,0.9436933,0.01490854,0.03741386,0.00199815],"study_design_scores_gemma":[0.0004816213,0.0001502011,0.004838726,0.00001033905,0.0000271065,0.00002275183,0.00008826442,0.0003924295,0.275021,0.0002955589,0.7183919,0.0002800985],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5333211,0.08091336,0.01913422,0.103882,0.001337397,0.002188599,0.001324565,0.0005754833,0.2573233],"genre_scores_gemma":[0.9858352,0.0005840955,0.007207316,0.004989265,0.0003597496,0.00005056566,0.0007211845,0.00001963691,0.0002330045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.680978,"threshold_uncertainty_score":0.4882666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03970417134223923,"score_gpt":0.2816704604476527,"score_spread":0.2419662891054135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}