{"id":"W3012577655","doi":"10.1161/jaha.119.015197","title":"Associations of Peripheral Artery Disease With Calf Skeletal Muscle Mitochondrial DNA Heteroplasmy","year":2020,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; Office of Dietary Supplements","keywords":"Heteroplasmy; Mitochondrial DNA; Skeletal muscle; Mitochondrial disease; Arterial disease; Peripheral; Biology; Medicine; Genetics; Cardiology; Internal medicine; Gene; Vascular disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005843953,0.0002422633,0.0002425198,0.0005946463,0.0003154011,0.0004334695,0.0003088526,0.0003809992,0.002453641],"category_scores_gemma":[0.003464905,0.0001369695,0.0002228575,0.0006452085,0.0002512505,0.0001976511,0.0003694885,0.000448268,0.0001297223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000130355,"about_ca_system_score_gemma":0.0001580982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001966498,"about_ca_topic_score_gemma":0.001830418,"domain_scores_codex":[0.99965,0.00008973511,0.00004066915,0.00009441181,0.00005296745,0.00007235209],"domain_scores_gemma":[0.9963142,0.001201434,0.001510059,0.0001669846,0.0002576584,0.0005496864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001177569,0.00001226252,0.9985733,0.000007728021,0.00003371838,0.00008713706,0.00001214427,0.00004158355,0.0002435339,0.00001181861,0.00002169965,0.0008373566],"study_design_scores_gemma":[0.000003461228,0.00009262518,0.9990694,0.000003529484,0.00002138599,0.0004354383,0.00002404519,0.0002302203,0.00005099204,0.00002948625,0.00003798137,0.000001363251],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989713,0.0003969525,0.000194618,0.00004117967,0.000004942416,0.0000036339,0.0001099933,0.000004600924,0.0002727029],"genre_scores_gemma":[0.9997136,0.00006307357,0.00007102991,0.000008029564,0.00000848442,0.000001996436,0.00007207137,7.395492e-7,0.00006087753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002453641,"threshold_uncertainty_score":0.008208275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01086650595541797,"score_gpt":0.2416776615619524,"score_spread":0.2308111556065345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}