{"id":"W3012705781","doi":"10.4049/jimmunol.1901481","title":"Galectin-9 and VISTA Expression Define Terminally Exhausted T Cells in HIV-1 Infection","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research","keywords":"TIGIT; Downregulation and upregulation; Galectin; Cytotoxic T cell; Biology; Degranulation; CD8; Molecular biology; ZAP70; IL-2 receptor; T-cell receptor; T cell; Interleukin 21; CD28; CD44; Receptor; Immunology; Cell biology; Cell; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006238424,0.0001818316,0.0001547058,0.0003352718,0.0001200642,0.0003567679,0.00007832637,0.0002832097,0.001191826],"category_scores_gemma":[0.0001119479,0.000137266,0.0001311518,0.0001813475,0.0001496601,0.0001400564,0.0002170832,0.0003174543,0.0001781136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008772407,"about_ca_system_score_gemma":0.0000276701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001338308,"about_ca_topic_score_gemma":0.000111971,"domain_scores_codex":[0.9999349,0.00001506862,0.000006351012,0.00001392666,0.00001295475,0.00001673645],"domain_scores_gemma":[0.9999533,0.000008329554,0.0000138516,0.000004229674,0.000005633134,0.00001470947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003685585,0.00002986967,0.01550105,0.00003903944,0.00001591726,0.0005017137,0.00008005172,0.00007002807,0.9806938,0.00005796105,0.00002363059,0.002618432],"study_design_scores_gemma":[0.00007658861,0.002031412,0.5611781,0.00004757372,0.00012403,0.01757424,0.0005055382,0.004135254,0.4098611,0.0006656231,0.003768198,0.00003216219],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987242,0.0005296469,0.0003254245,0.000007073174,0.000002871897,0.000009598402,0.00007687174,0.000007351305,0.0003170652],"genre_scores_gemma":[0.9990816,0.0001772446,0.0003646894,0.00001329524,0.000005099566,0.000006600147,0.0001191528,0.000002002801,0.000230354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001191826,"threshold_uncertainty_score":0.003987074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119523425925508,"score_gpt":0.2208920335131953,"score_spread":0.2096967992539402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}