{"id":"W3012705781","doi":"10.4049/jimmunol.1901481","title":"Galectin-9 and VISTA Expression Define Terminally Exhausted T Cells in HIV-1 Infection","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research","keywords":"TIGIT; Downregulation and upregulation; Galectin; Cytotoxic T cell; Biology; Degranulation; CD8; Molecular biology; ZAP70; IL-2 receptor; T-cell receptor; T cell; Interleukin 21; CD28; CD44; Receptor; Immunology; Cell biology; Cell; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003801102,0.0001397529,0.0003399955,0.0001209071,0.0001020607,0.00000728431,0.000207335,0.0002238865,0.0002313489],"category_scores_gemma":[0.000100197,0.00009115235,0.00005627084,0.0001704677,0.0002416029,0.00006970125,0.0001102626,0.000719619,0.00006084466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003355672,"about_ca_system_score_gemma":0.00006263953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006200613,"about_ca_topic_score_gemma":0.00003612103,"domain_scores_codex":[0.9986426,0.0005099136,0.0004488624,0.000126258,0.00002419493,0.0002481834],"domain_scores_gemma":[0.9992336,0.0001749069,0.000366812,0.0001248719,0.00007989007,0.00001989046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001312779,0.00005003109,0.007337912,0.000009986857,0.00007397673,0.00001254234,0.0009343479,0.00001475397,0.9847153,0.0000279552,0.00212228,0.003388145],"study_design_scores_gemma":[0.005695219,0.003871852,0.2047367,0.0001152779,0.0001323214,0.00394434,0.0007983201,0.000009469642,0.7170525,0.0002137903,0.06313549,0.0002947093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990402,0.006743567,0.0002571083,0.001668573,0.0005470436,0.00009658979,0.00000337797,0.00001303933,0.0002686805],"genre_scores_gemma":[0.9973804,0.001893873,0.00004920441,0.0003940931,0.00005838288,0.000002183369,0.00000345478,0.0000104663,0.0002078996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2676628,"threshold_uncertainty_score":0.3717085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119523425925508,"score_gpt":0.2208920335131953,"score_spread":0.2096967992539402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}