{"id":"W3012861332","doi":"10.1073/pnas.1920193117","title":"15-Epi-LXA <sub>4</sub> and 17-epi-RvD1 restore TLR9-mediated impaired neutrophil phagocytosis and accelerate resolution of lung inflammation","year":2020,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research; Government of Canada; Yale University","keywords":"Phagocytosis; Inflammation; Apoptosis; Neutrophil extracellular traps; Biology; Granulocyte; Immunology; Receptor; Innate immune system; Microbiology; Cell biology; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001375966,0.0002312322,0.0002966209,0.0001716102,0.00008377646,0.0002316312,0.0001593682,0.000244407,0.002430788],"category_scores_gemma":[0.0001034426,0.000112421,0.0002018423,0.00007630617,0.0003125097,0.0001813994,0.0001800967,0.0006026708,0.0005625574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002550723,"about_ca_system_score_gemma":0.0002239572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003411696,"about_ca_topic_score_gemma":0.0004241748,"domain_scores_codex":[0.9998888,0.00002391168,0.00001549239,0.00001329395,0.00002418157,0.00003432858],"domain_scores_gemma":[0.9999173,0.00001158,0.00002173128,0.000009896064,0.000006008538,0.00003355739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001594807,0.0001774878,0.0002087535,0.0000512005,0.00001015888,0.0000685974,0.00001292817,0.0001088502,0.9949503,0.0001658074,0.00006747562,0.002583611],"study_design_scores_gemma":[0.00007098616,0.001424736,0.002121212,0.000004578726,0.000013776,0.0002402544,0.00003192982,0.0005425816,0.9933339,0.00006945858,0.002143361,0.000003322144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960285,0.0009887142,0.00137931,0.0001088259,0.00004518453,0.00002222026,0.0002947051,0.00006729343,0.001065228],"genre_scores_gemma":[0.9928709,0.0004904178,0.001976092,0.00008248955,0.00001287764,0.00003104224,0.000564282,0.00001858414,0.003953337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002430788,"threshold_uncertainty_score":0.008131802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0313649025231726,"score_gpt":0.25766139822519,"score_spread":0.2262964957020174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}