{"id":"W3012861332","doi":"10.1073/pnas.1920193117","title":"15-Epi-LXA <sub>4</sub> and 17-epi-RvD1 restore TLR9-mediated impaired neutrophil phagocytosis and accelerate resolution of lung inflammation","year":2020,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research; Government of Canada; Yale University","keywords":"Phagocytosis; Inflammation; Apoptosis; Neutrophil extracellular traps; Biology; Granulocyte; Immunology; Receptor; Innate immune system; Microbiology; Cell biology; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009958609,0.0001244213,0.0002394341,0.0001923624,0.0002503893,0.00001854885,0.0002951398,0.0001951187,0.000007820907],"category_scores_gemma":[0.0008486835,0.00009344739,0.0000537311,0.0005506051,0.0008965501,0.0006749697,0.0001526068,0.0002022553,0.000002047595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002625271,"about_ca_system_score_gemma":0.00004773594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000769616,"about_ca_topic_score_gemma":1.40959e-7,"domain_scores_codex":[0.9988099,0.00004144551,0.000509941,0.0002422222,0.0002315899,0.0001649243],"domain_scores_gemma":[0.9987997,0.0001721049,0.00069015,0.00001191407,0.0003032506,0.00002286326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002620296,0.00001348923,0.002672385,0.0001097524,0.00003787339,8.452503e-9,0.0006535722,0.00002564869,0.9919388,0.00250718,0.0006473311,0.00113191],"study_design_scores_gemma":[0.0005243308,0.0001260468,0.1043796,0.0001143321,0.00002992871,0.000008436563,0.0001510822,0.001104173,0.892089,0.001221247,0.0001686231,0.00008324223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922178,0.001251478,0.000001473047,0.005994319,0.00002281365,0.0002576421,0.00001554364,0.00001843232,0.0002205215],"genre_scores_gemma":[0.9991673,0.0005416155,0.00006769723,0.0001507607,0.00004060409,0.000009954968,0.000003528964,0.000004840426,0.00001372413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1017072,"threshold_uncertainty_score":0.3810674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0313649025231726,"score_gpt":0.25766139822519,"score_spread":0.2262964957020174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}