{"id":"W3013137224","doi":"10.1038/s41556-020-0499-7","title":"Setting the chromatin stage in oocytes","year":2020,"lang":"en","type":"letter","venue":"Nature Cell Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Demethylase; Reprogramming; Cell biology; Histone; Chromatin; Epigenetics; Demethylation; Maternal to zygotic transition; Biology; Histone methylation; Histone code; Zygote; Chemistry; Embryo; Genetics; Embryogenesis; DNA methylation; Gene; Nucleosome; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00385988,0.0004090471,0.000739973,0.0004181199,0.002552995,0.002657727,0.001424774,0.02319118,0.003902033],"category_scores_gemma":[0.01304442,0.0004693274,0.0006785428,0.0002289402,0.00412914,0.003300644,0.001653741,0.02042638,0.002247287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00296421,"about_ca_system_score_gemma":0.001450696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002673105,"about_ca_topic_score_gemma":0.005458928,"domain_scores_codex":[0.9986629,0.0004159821,0.00008320476,0.0002087564,0.0004228356,0.0002062594],"domain_scores_gemma":[0.9968464,0.002128958,0.0001519412,0.000152339,0.0002359356,0.0004844645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000429865,0.00003255353,0.0005468069,0.000096428,0.0000299155,0.002140933,0.000212022,0.0001965991,0.001814617,0.03264466,0.9395275,0.02232815],"study_design_scores_gemma":[0.0002380195,0.00009348084,0.0008368624,0.000120977,0.00002435586,0.001157401,0.0003586326,0.000542324,0.002775954,0.06230872,0.9314821,0.00006128343],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001334816,0.007285216,0.0005075592,0.9416845,0.04299713,0.00001290138,0.00005763245,0.00005445884,0.006065877],"genre_scores_gemma":[0.02648159,0.005432571,0.0006435827,0.8837357,0.06444976,0.00005853168,0.00003989333,0.00006672803,0.01909167],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02319118,"threshold_uncertainty_score":0.02150697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006725005834718497,"score_gpt":0.2518089749991557,"score_spread":0.2450839691644372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}