{"id":"W3013160452","doi":"10.3389/fcimb.2020.00123","title":"Verotoxin Receptor-Based Pathology and Therapies","year":2020,"lang":"en","type":"review","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Shiga toxin; Endoplasmic-reticulum-associated protein degradation; Globotriaosylceramide; Transferrin receptor; Endosome; Biology; Cell biology; Protein subunit; Ganglioside; Furin; Lipid raft; Endoplasmic reticulum; Transferrin; Biochemistry; Unfolded protein response; Intracellular; Escherichia coli; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002656794,0.0003673562,0.0009783981,0.0001870739,0.00009452848,0.00002167123,0.0001152375,0.0006778846,0.00001114953],"category_scores_gemma":[0.0001084294,0.0003226005,0.0001561728,0.0001695403,0.0004360399,0.000003434642,0.0002107011,0.0004132829,0.000005712714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000409908,"about_ca_system_score_gemma":0.0001336358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001245235,"about_ca_topic_score_gemma":0.0000126688,"domain_scores_codex":[0.9980268,0.0006183346,0.0003354973,0.0006695468,0.00002980353,0.0003200436],"domain_scores_gemma":[0.9995128,0.00003154564,0.0001422948,0.0002070741,0.00003437423,0.00007189527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001314056,0.0001505131,0.004406273,0.006026499,0.0007048393,0.00006017719,0.0001085009,0.000001317807,0.09646063,0.00003192602,0.02082518,0.8710927],"study_design_scores_gemma":[0.0004395212,0.0003814249,0.00001378961,0.0002334581,0.00006223006,0.00004829799,0.00001578267,0.00000537992,0.0006843883,0.0000129151,0.9978051,0.0002977448],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001961872,0.9948283,0.001824898,0.00005995567,0.0005586488,0.000616766,0.00005737151,0.00001591194,0.00007624439],"genre_scores_gemma":[0.0002537086,0.9973947,0.001289121,0.0001217784,0.0001642383,0.0001589312,0.0004698811,0.00003977039,0.0001078826],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9769799,"threshold_uncertainty_score":0.9999226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01474638010016277,"score_gpt":0.2704260370377323,"score_spread":0.2556796569375696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}