{"id":"W3013202726","doi":"10.1101/2020.03.24.000620","title":"A long noncoding RNA, <i>LOC157273</i> , is the effector transcript at the chromosome 8p23.1- <i>PPP1R3B</i> metabolic traits and type 2 diabetes risk locus","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University and Génome Québec Innovation Centre","funders":"","keywords":"Gene knockdown; Biology; Locus (genetics); Gene; Exon; Gene expression; Molecular biology; Transcriptome; Messenger RNA; RNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001253595,0.0004747715,0.0003603627,0.0002665953,0.0002340595,0.0002688512,0.0002332203,0.0003940813,0.004179751],"category_scores_gemma":[0.0002270518,0.0001427725,0.0004807234,0.0002203753,0.0003384248,0.00009238756,0.0002386791,0.0003969816,0.001123433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000232192,"about_ca_system_score_gemma":0.0001991829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009031059,"about_ca_topic_score_gemma":0.001337477,"domain_scores_codex":[0.9998147,0.00002230398,0.00001368227,0.00008078881,0.00004830091,0.00002023107],"domain_scores_gemma":[0.9997452,0.00004594467,0.000134345,0.00001809794,0.00001740804,0.00003899259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002127238,0.00001646474,0.003593236,0.00005760225,0.00003188433,0.0007809298,0.00002352001,0.0001399244,0.9921638,0.0001861608,0.0003044905,0.002489061],"study_design_scores_gemma":[0.0002073979,0.0007603017,0.2012525,0.00008830422,0.0002603658,0.00635052,0.0001812139,0.005060663,0.7710484,0.0007856663,0.01394126,0.00006343075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832049,0.001156579,0.009691698,0.0002539231,0.0001318439,0.00004056419,0.003293141,0.0003618045,0.001865531],"genre_scores_gemma":[0.9922712,0.0002129116,0.003254644,0.0002106317,0.00003595735,0.00005754084,0.001922365,0.0001023761,0.001932351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004179751,"threshold_uncertainty_score":0.01398265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009503797273787707,"score_gpt":0.2198772758705449,"score_spread":0.2103734785967572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}