{"id":"W3013385399","doi":"10.3390/antibiotics9030136","title":"Virulence-Inhibiting Herbal Compound Falcarindiol Significantly Reduced Mortality in Mice Infected with Pseudomonas aeruginosa","year":2020,"lang":"en","type":"article","venue":"Antibiotics","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Science Foundation of Shaanxi Provincial Department of Education; Natural Science Foundation of Shaanxi Province","keywords":"Virulence; Pseudomonas aeruginosa; Microbiology; Quorum sensing; Swarming motility; Pyocyanin; Biology; Gene; Biofilm; Bacteria; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007582743,0.0005032883,0.0003672055,0.0004141376,0.000128036,0.0001273786,0.0001636033,0.0002400356,0.001077238],"category_scores_gemma":[0.0000988578,0.00009826456,0.0001824854,0.0001597274,0.0002122457,0.0001993015,0.0001089944,0.0005948273,0.000110384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001322348,"about_ca_system_score_gemma":0.0002105407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004728017,"about_ca_topic_score_gemma":0.0007354463,"domain_scores_codex":[0.9999475,0.000008220241,0.000004314595,0.000008553994,0.000009949263,0.00002144909],"domain_scores_gemma":[0.9999259,0.00001088757,0.00001936999,0.000004953587,0.00001030649,0.0000287358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001237507,0.0003443378,0.0003032697,0.00008762281,0.000009975267,0.00006368321,0.000013849,0.00007382585,0.9926988,0.00003343631,0.00007860437,0.005055164],"study_design_scores_gemma":[0.0002401856,0.007592565,0.01086807,0.0000167906,0.00006659799,0.000227468,0.00004517407,0.0008415888,0.9778383,0.00006022643,0.002193326,0.00000975377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964591,0.001365724,0.0007120831,0.0001568217,0.00003411368,0.00003638833,0.0002375137,0.00009996264,0.0008983504],"genre_scores_gemma":[0.9946456,0.001432098,0.001104428,0.0001240992,0.00002049963,0.0000571423,0.0004817634,0.0000149372,0.002119304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001077238,"threshold_uncertainty_score":0.003603697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02315346850862477,"score_gpt":0.2427769289396061,"score_spread":0.2196234604309814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}