{"id":"W3013447738","doi":"10.1182/blood.2020004856","title":"Venetoclax plus LDAC for newly diagnosed AML ineligible for intensive chemotherapy: a phase 3 randomized placebo-controlled trial","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":756,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal","funders":"Genentech","keywords":"Venetoclax; Medicine; Internal medicine; Neutropenia; Febrile neutropenia; Hazard ratio; Chemotherapy regimen; Cytarabine; Adverse effect; Chemotherapy; Surgery; Oncology; Leukemia; Confidence interval; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001587703,0.001043972,0.00205886,0.0003228785,0.0003873439,0.0009647415,0.000646455,0.001486912,0.004692061],"category_scores_gemma":[0.001566171,0.0003977567,0.001614662,0.0003652982,0.0008327203,0.0006589426,0.0002715916,0.002382089,0.0004895843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004783426,"about_ca_system_score_gemma":0.000940063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005462531,"about_ca_topic_score_gemma":0.001630521,"domain_scores_codex":[0.9995186,0.0002988992,0.00002183689,0.00007077178,0.0000289543,0.00006099082],"domain_scores_gemma":[0.999042,0.0003461042,0.0002589223,0.00006546966,0.00004324921,0.0002442622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.974676,0.005249606,0.0004307607,0.000717008,0.0006143866,0.00004637715,0.00004469022,0.0001946735,0.002811723,0.0001137668,0.0006170532,0.014484],"study_design_scores_gemma":[0.9611888,0.03653907,0.0009500706,0.00004526127,0.0002779743,0.00003101517,0.00001369892,0.0002222414,0.0002266312,0.0001038653,0.0003932339,0.000008150794],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981925,0.009740168,0.0008154697,0.0007611361,0.0004894596,0.003534127,0.0007525316,0.0001591364,0.001823048],"genre_scores_gemma":[0.9845819,0.004913744,0.001920186,0.001475423,0.0004859988,0.004314231,0.000639363,0.00002375876,0.00164547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004692061,"threshold_uncertainty_score":0.01569647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0321181257161765,"score_gpt":0.3360420507156437,"score_spread":0.3039239249994672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}