{"id":"W3013453726","doi":"10.1158/2326-6074.tumimm19-b62","title":"Abstract B62: Development of novel chimeric antigen receptor T cells for immunotherapy of hepatocellular carcinoma","year":2020,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Epitope; Monoclonal antibody; Antigen; Immunotherapy; Effector; Cancer immunotherapy; Immunohistochemistry; Cancer research; Hepatocellular carcinoma; Antibody; Adoptive cell transfer; Molecular biology; T cell; Biology; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001225075,0.0002402643,0.0008120787,0.000384159,0.0001574581,0.00001158487,0.0006128369,0.0002664512,0.004547721],"category_scores_gemma":[0.0001462684,0.0002244736,0.0002265992,0.0009034806,0.0007889404,0.00005992011,0.0001867253,0.000768898,0.00004076722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002832588,"about_ca_system_score_gemma":0.002218289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003651053,"about_ca_topic_score_gemma":0.000006418824,"domain_scores_codex":[0.9969256,0.0001175774,0.0007859907,0.0005464946,0.0007677582,0.0008566157],"domain_scores_gemma":[0.9975333,0.0003646761,0.0001970005,0.0006053393,0.001115854,0.0001838392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005234603,0.0003901666,0.01515358,0.0005398272,0.0007068876,0.000005451748,0.002925737,0.00000283202,0.9293572,0.00002336433,0.0008121874,0.04484819],"study_design_scores_gemma":[0.004583401,0.001014797,0.02873416,0.000114454,0.0000118777,0.000003590806,0.0005777988,0.0002090491,0.9135219,0.000005922072,0.05105644,0.0001665535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854594,0.01007512,0.0004015121,0.001273247,0.0001854595,0.001991083,0.00008444957,0.00002859439,0.0005011682],"genre_scores_gemma":[0.9910414,0.002543479,0.004318699,0.0000892091,0.0001779204,0.0004055293,0.00005845066,0.00009421136,0.001271057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05024426,"threshold_uncertainty_score":0.9963623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1458943262138125,"score_gpt":0.3910327011213851,"score_spread":0.2451383749075726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}