{"id":"W3013453726","doi":"10.1158/2326-6074.tumimm19-b62","title":"Abstract B62: Development of novel chimeric antigen receptor T cells for immunotherapy of hepatocellular carcinoma","year":2020,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Epitope; Monoclonal antibody; Antigen; Immunotherapy; Effector; Cancer immunotherapy; Immunohistochemistry; Cancer research; Hepatocellular carcinoma; Antibody; Adoptive cell transfer; Molecular biology; T cell; Biology; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009492757,0.0002699184,0.0001731108,0.000128019,0.00007112588,0.0001492903,0.0001388756,0.000329094,0.001083216],"category_scores_gemma":[0.00007088875,0.00007252044,0.0001586007,0.00007317518,0.00007107055,0.0001181547,0.000117851,0.0003959898,0.0004272993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001339724,"about_ca_system_score_gemma":0.0001361901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002455293,"about_ca_topic_score_gemma":0.0002615307,"domain_scores_codex":[0.9999369,0.00001214781,0.000004199733,0.00001250656,0.00001747154,0.00001675473],"domain_scores_gemma":[0.9999733,0.000002999772,0.000005102336,0.000002746491,0.000006104367,0.000009769424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002093569,0.0001148269,0.000278787,0.00006024426,0.000009457352,0.00009132651,0.00001643251,0.0004809486,0.9886041,0.0001167931,0.0002011823,0.009816638],"study_design_scores_gemma":[0.000630512,0.007102307,0.008304023,0.00003636784,0.0001162529,0.001772275,0.00004025362,0.01084957,0.9487398,0.0002308864,0.02215664,0.00002110981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890266,0.002437935,0.00573675,0.0001485437,0.00006336164,0.0001055995,0.0001407136,0.0001271772,0.002213382],"genre_scores_gemma":[0.9880165,0.001121023,0.00720073,0.0001157035,0.00003569751,0.0000711461,0.0004550049,0.00001236942,0.002971858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001083216,"threshold_uncertainty_score":0.003623724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1458943262138125,"score_gpt":0.3910327011213851,"score_spread":0.2451383749075726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}