{"id":"W3013739803","doi":"10.1016/j.ajo.2020.03.020","title":"Faster Sensitivity Loss around Dense Scotomas than for Overall Macular Sensitivity in Stargardt Disease: ProgStar Report No. 14","year":2020,"lang":"en","type":"article","venue":"American Journal of Ophthalmology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Daiichi Sankyo Europe; Spark Therapeutics; Allergan; University of California, Los Angeles; Telemedicine and Advanced Technology Research Center; Foundation Fighting Blindness; Genentech; Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften; Novartis; Moorfields Eye Hospital NHS Foundation Trust; University of Pennsylvania; Omeros Corporation; Novo Nordisk; Boehringer Ingelheim; Austrian Science Fund; Heidelberg Engineering; Apellis Pharmaceuticals; Medizinische Universität Graz; Medical Research and Materiel Command; Duke Clinical Research Institute; Astellas Pharma; Ionis Pharmaceuticals; Universität Basel; Carl Zeiss Meditec AG; Johns Hopkins University; David Geffen School of Medicine, University of California, Los Angeles; Case Western Reserve University; F. Hoffmann-La Roche; NightstaRx; Sanofi; Karl-Franzens-Universität Graz","keywords":"Microperimetry; Medicine; Stargardt disease; Blind spot; Central scotoma; Ophthalmology; Cohort; Prospective cohort study; Optometry; Surgery; Retinal; Internal medicine; Visual acuity; Artificial intelligence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001710461,0.0003704383,0.0003247348,0.001316973,0.00024358,0.000602726,0.0002632652,0.00033631,0.001847185],"category_scores_gemma":[0.00306978,0.0001843221,0.0004694501,0.0004993732,0.0003013475,0.0005244891,0.0004518455,0.0002885465,0.0003780785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003130567,"about_ca_system_score_gemma":0.0001710317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001624539,"about_ca_topic_score_gemma":0.001594236,"domain_scores_codex":[0.9992771,0.0001473019,0.00007908142,0.0002440414,0.0002089272,0.0000436054],"domain_scores_gemma":[0.9972114,0.0007982678,0.001093174,0.0004133242,0.0003663984,0.0001174845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000902272,0.00003262468,0.9673309,0.00007641124,0.0001074067,0.0005873038,0.0001152928,0.0001969365,0.004627088,0.00006883433,0.0003345442,0.02562022],"study_design_scores_gemma":[0.00001883833,0.0003469718,0.9941697,0.00001104299,0.00005092104,0.002802994,0.00004037855,0.0004277564,0.001626077,0.00008164062,0.0004141718,0.000009444308],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965658,0.000632206,0.001087235,0.00003083996,0.0000134558,0.00003365137,0.0004756509,0.00005560615,0.001105495],"genre_scores_gemma":[0.9988056,0.0001018373,0.0004607836,0.00001950127,0.00001106526,0.000009318946,0.0003139282,0.00001029587,0.0002675847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001847185,"threshold_uncertainty_score":0.009045899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307048475616954,"score_gpt":0.2691433021674006,"score_spread":0.2560728174112311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}