{"id":"W3013950939","doi":"10.1038/s41565-020-0660-2","title":"Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry","year":2020,"lang":"en","type":"article","venue":"Nature Nanotechnology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":128,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Einstein Stiftung Berlin; Deutsche Forschungsgemeinschaft","keywords":"Capsid; Virus; Viral envelope; Biophysics; In vivo; Viral entry; Cell biology; Viral replication; Virology; In vitro; Bacteriophage; Biology; Chemistry; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003866828,0.0001923106,0.0001914553,0.00003710292,0.0001306315,0.0000296497,0.0002928639,0.0004332451,0.000667388],"category_scores_gemma":[0.00004811409,0.0001551387,0.00004889175,0.0003842569,0.0002020201,0.0001395016,0.0002146731,0.0007124592,0.0005853687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008092886,"about_ca_system_score_gemma":0.00001159547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008462792,"about_ca_topic_score_gemma":0.0004114799,"domain_scores_codex":[0.9988991,0.00001952138,0.0001888348,0.0004098753,0.0001380366,0.0003446143],"domain_scores_gemma":[0.9995253,0.00002080175,0.00009029056,0.0002509736,0.00001168935,0.000100936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000937864,0.00007264013,0.0006429285,0.000005925177,0.00002638538,0.00004652208,0.000192239,0.00006009447,0.9920348,0.0001062716,0.003668579,0.00304982],"study_design_scores_gemma":[0.0005833331,0.0002229551,0.001936957,0.00001005086,0.00003007354,0.00005162852,0.0000566158,0.00002426097,0.7786597,0.0000409921,0.2182115,0.0001719462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907888,0.0003436305,0.0000528097,0.007167758,0.0001430212,0.0002363211,0.00001755768,0.0002399439,0.001010149],"genre_scores_gemma":[0.9921336,0.00003637857,0.001175786,0.006399038,0.00004776619,0.00002272274,0.000004606257,0.0000217514,0.000158348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2145429,"threshold_uncertainty_score":0.7523926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007359125012792596,"score_gpt":0.222699079707584,"score_spread":0.2153399546947914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}