{"id":"W3014050626","doi":"10.1016/j.molimm.2020.03.010","title":"Glycosylation of Fcγ receptors influences their interaction with various IgG1 glycoforms","year":2020,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Polytechnique Montréal; National Research Council Canada","funders":"Institut TransMedTech; National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Canada First Research Excellence Fund","keywords":"Glycan; Glycosylation; Fragment crystallizable region; Immunoglobulin G; Chemistry; Fc receptor; Receptor; Antibody; Surface plasmon resonance; Immunoglobulin Fc Fragments; Monoclonal antibody; Context (archaeology); N-linked glycosylation; Molecular biology; Biochemistry; Biology; Glycoprotein; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002045334,0.000247289,0.0001320386,0.0001169566,0.0001632613,0.0003701547,0.0002004063,0.000223944,0.001874225],"category_scores_gemma":[0.000384165,0.0001590048,0.0003236792,0.0001328216,0.000218861,0.0001990045,0.0001772952,0.0004696863,0.0002156373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000433646,"about_ca_system_score_gemma":0.0001794614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002070545,"about_ca_topic_score_gemma":0.001809693,"domain_scores_codex":[0.9998181,0.00004273288,0.000009621406,0.00001994064,0.00002566288,0.00008390536],"domain_scores_gemma":[0.9998844,0.00004556531,0.000017493,0.00001207697,0.00001639861,0.00002397069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006222119,0.0000286719,0.0008774631,0.00002236322,0.00001003098,0.0000435171,0.00003219174,0.00008663212,0.9971611,0.0001590139,0.00004185821,0.0009149835],"study_design_scores_gemma":[0.00003176733,0.0002470768,0.02291254,0.00001243663,0.00004735304,0.0001747716,0.00009528603,0.001382062,0.9736771,0.0001033469,0.001306932,0.000009262407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989785,0.0001764381,0.000234643,0.00002313435,0.00000758278,0.000002805655,0.00004062005,0.000003685605,0.0005327374],"genre_scores_gemma":[0.9987342,0.0001822383,0.0002691605,0.00005114669,0.000004774058,0.000003654743,0.000119253,0.000007796606,0.0006278842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002070545,"threshold_uncertainty_score":0.006269932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02023962400486415,"score_gpt":0.2778907808009685,"score_spread":0.2576511567961043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}