{"id":"W3014144739","doi":"10.3390/ijms21072417","title":"Transcriptomic Profiling in Fins of Atlantic Salmon Parasitized with Sea Lice: Evidence for an Early Imbalance Between Chalimus-Induced Immunomodulation and the Host’s Defense Response","year":2020,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Parasite Biology and Host Interactions","field":"Environmental Science","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island; Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Ocean Frontier Institute","keywords":"Biology; Transcriptome; Immune system; Microarray; Microarray analysis techniques; Downregulation and upregulation; Gene expression profiling; Immunity; Fold change; Immunology; Gene expression; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001062864,0.00007494848,0.0001505856,0.00006429285,0.00006963911,0.00004089578,0.0004059854,0.00003339498,0.000006924635],"category_scores_gemma":[0.0002628803,0.00004878448,0.00005411651,0.0001524622,0.0003338316,0.0004573268,0.00002533465,0.000118493,0.000001322574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003798088,"about_ca_system_score_gemma":0.00005256202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002036401,"about_ca_topic_score_gemma":0.0000482538,"domain_scores_codex":[0.998895,0.0002376802,0.0002932346,0.0001567551,0.0003139167,0.0001033482],"domain_scores_gemma":[0.999123,0.0004367758,0.0002795269,0.00005663086,0.00005734856,0.00004666893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004653427,0.00002026699,0.4532814,0.000002017969,0.00002886017,0.0000095741,0.00107526,0.0008340404,0.5396326,0.0001045538,7.171065e-7,0.0003573411],"study_design_scores_gemma":[0.001404938,0.001137309,0.9464586,0.00009441651,0.00002734242,0.00004586319,0.0001790202,0.003592307,0.04680953,0.0001641764,0.00001068703,0.00007579552],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932271,0.000114411,0.003058265,0.003317149,0.0000670938,0.0001829504,0.000005656448,0.000003001467,0.0000243322],"genre_scores_gemma":[0.9985031,0.00002485141,0.00125896,0.0001730216,0.00002776918,0.000005386405,0.000001126042,0.000003357489,0.000002358737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4931772,"threshold_uncertainty_score":0.1989373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05444327727192372,"score_gpt":0.3621841751527621,"score_spread":0.3077408978808384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}