{"id":"W3014176044","doi":"10.1186/s12985-020-01304-2","title":"The USP18 cysteine protease promotes HBV production independent of its protease activity","year":2020,"lang":"en","type":"article","venue":"Virology Journal","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine; Department of Science and Technology of Sichuan Province; Massachusetts General Hospital","keywords":"Biology; Protease; Virology; Cysteine protease; Microbiology; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001865942,0.0002640739,0.000224151,0.0001745841,0.000133235,0.0002981327,0.0001103345,0.0002170143,0.001960886],"category_scores_gemma":[0.0001566495,0.0001100183,0.0003469042,0.0001119926,0.0002651807,0.000198711,0.0001837613,0.0004840412,0.0004061491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001940751,"about_ca_system_score_gemma":0.0001694998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001705721,"about_ca_topic_score_gemma":0.0001949399,"domain_scores_codex":[0.9998318,0.0000296228,0.00002136795,0.00003534939,0.00005005142,0.0000317699],"domain_scores_gemma":[0.9998103,0.00003177334,0.00006294559,0.00002536595,0.00003102654,0.00003873818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002096195,0.00003109578,0.0004568175,0.00006922249,0.000005351067,0.00005688258,0.00001354426,0.00002016048,0.9976381,0.00009848309,0.00006538502,0.00133531],"study_design_scores_gemma":[0.00002552905,0.0003281481,0.005231746,0.00001173277,0.00002146357,0.0003427302,0.00002386296,0.0006956894,0.9896832,0.000065543,0.003566296,0.000004123218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925492,0.002644543,0.002696921,0.0001600853,0.00005560208,0.00002929546,0.0003659498,0.00008245464,0.001415974],"genre_scores_gemma":[0.9950311,0.0009674288,0.001845591,0.00004080025,0.00002326749,0.00002412664,0.0004378157,0.000014552,0.001615333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001960886,"threshold_uncertainty_score":0.006559789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03580050803478745,"score_gpt":0.2848987668874827,"score_spread":0.2490982588526953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}