{"id":"W3014192555","doi":"10.1016/j.cub.2020.02.083","title":"Amyloid Beta Secreted during Consolidation Prevents Memory Malleability","year":2020,"lang":"en","type":"article","venue":"Current Biology","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Malleability; Amyloid (mycology); Amyloid beta; Memory consolidation; Consolidation (business); Cell biology; Neuroscience; Biochemistry; Computer science; Botany; Peptide; Business","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005095063,0.001010458,0.001432189,0.0005326962,0.0003847542,0.001359143,0.00110407,0.00111108,0.002900361],"category_scores_gemma":[0.001002007,0.0006219975,0.0006642609,0.0003273233,0.001752433,0.001206098,0.0007127907,0.003816957,0.00130577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006070466,"about_ca_system_score_gemma":0.001572888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001224779,"about_ca_topic_score_gemma":0.001598758,"domain_scores_codex":[0.9994876,0.00006656929,0.00005560779,0.00007291696,0.00008824905,0.0002288921],"domain_scores_gemma":[0.9986739,0.0001747323,0.0002533641,0.0002766938,0.0001201666,0.0005012233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.016218,0.001464648,0.00079106,0.000200574,0.0001735999,0.0003044804,0.0001650628,0.0001956542,0.9671049,0.0003531394,0.0006185596,0.01241031],"study_design_scores_gemma":[0.001435134,0.007391187,0.01344795,0.00007030619,0.0002212566,0.0007463354,0.0004089046,0.001612413,0.9708245,0.00142279,0.002373587,0.00004568484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941958,0.002404631,0.0009334586,0.0003828987,0.0005050453,0.0000368496,0.0002519902,0.0002163631,0.001072949],"genre_scores_gemma":[0.992448,0.001537064,0.000857746,0.0001702214,0.0001192316,0.00007298684,0.0004942596,0.0000835453,0.004216897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002900361,"threshold_uncertainty_score":0.009702682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06671339862805703,"score_gpt":0.3567314269295683,"score_spread":0.2900180283015113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}