{"id":"W3014201940","doi":"10.1039/d0md00033g","title":"Unveiling the active isomer of cycloalanopine, a cyclic opine from <i>Lactobacillus rhamnosus</i> LS8, through synthesis and analog production","year":2020,"lang":"en","type":"article","venue":"RSC Medicinal Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lactobacillus rhamnosus; Production (economics); Lactobacillus; Chemistry; Stereochemistry; Food science; Economics; Fermentation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001243544,0.0003239574,0.0001397384,0.0001810107,0.0001247259,0.0003117048,0.0002547294,0.0002326207,0.001376948],"category_scores_gemma":[0.0002247613,0.00009986515,0.0001910475,0.000151773,0.0002112979,0.0002324511,0.0002337121,0.0004920365,0.0004364694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002186248,"about_ca_system_score_gemma":0.0003617499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000502162,"about_ca_topic_score_gemma":0.0007413731,"domain_scores_codex":[0.9999188,0.00001592014,0.00000807565,0.00001646544,0.00001781318,0.00002297162],"domain_scores_gemma":[0.9998872,0.00001388141,0.00002925542,0.0000189937,0.0000288847,0.00002183397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001328863,0.00003341578,0.0001302665,0.00006631295,0.000006741093,0.0002201978,0.00003483119,0.0001947944,0.9920449,0.0005175972,0.00009720768,0.006520735],"study_design_scores_gemma":[0.00002128114,0.0005929326,0.0003783283,0.000009738867,0.00001686745,0.0002515664,0.00004951997,0.0002577599,0.9909027,0.0000934405,0.007418432,0.000007369069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9761621,0.001513972,0.008804502,0.0002602667,0.0001041445,0.0001788938,0.0006964887,0.0001194628,0.01216017],"genre_scores_gemma":[0.9850482,0.001329407,0.009547795,0.0000795834,0.00001968892,0.00004060805,0.0005367786,0.00002886052,0.0033691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001376948,"threshold_uncertainty_score":0.004606366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01471705293310807,"score_gpt":0.2178394693814779,"score_spread":0.2031224164483698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}