{"id":"W3014225460","doi":"10.21037/cco.2020.03.03","title":"Prediction of Immune checkpoint inhibitors benefit from routinely measurable peripheral blood parameters","year":2020,"lang":"en","type":"review","venue":"Chinese Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Sault Area Hospital; Essar Steel Algoma (Canada)","funders":"","keywords":"Medicine; Peripheral blood; Immunotherapy; Immune system; Peripheral; Monoclonal antibody; Biomarker; Cancer immunotherapy; Cancer; Antibody; Oncology; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001140123,0.0008000599,0.001843179,0.001571277,0.0001013906,0.0009499539,0.0006363786,0.0006475186,0.001772827],"category_scores_gemma":[0.002738309,0.0001929839,0.0009930804,0.001241091,0.0002366071,0.0007263864,0.0003199348,0.001217989,0.0006660164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000388887,"about_ca_system_score_gemma":0.0006740351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006106712,"about_ca_topic_score_gemma":0.00101029,"domain_scores_codex":[0.999626,0.00009568964,0.00006110893,0.00008373337,0.0001113557,0.0000221367],"domain_scores_gemma":[0.9989234,0.0006923217,0.0001454383,0.00002264994,0.0001870211,0.00002912102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003814291,0.00008738074,0.00907733,0.009299566,0.0006686683,0.0001595334,0.00003651151,0.0007299455,0.001153519,0.001329692,0.008617194,0.9684592],"study_design_scores_gemma":[0.0003056285,0.002007796,0.08209523,0.02260783,0.007054775,0.00669649,0.0003061974,0.004573936,0.009312858,0.009433298,0.8553955,0.0002104761],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001733382,0.9957131,0.0006228351,0.0005030296,0.0001477622,0.00001391834,0.0001191715,0.00001168584,0.001135216],"genre_scores_gemma":[0.02344932,0.9728608,0.001437662,0.0005565103,0.0004638205,0.00004181708,0.0004048156,0.00000611495,0.0007791139],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001843179,"threshold_uncertainty_score":0.006029606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1278176220012243,"score_gpt":0.4020735567026682,"score_spread":0.2742559347014438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}