{"id":"W3014314607","doi":"10.1101/2020.04.01.020404","title":"The Parkinson’s Disease GWAS Locus Browser","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Common Fund; National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institute on Drug Abuse; Yale University; NIH Office of the Director; Alzheimer's Society; University of California, San Francisco; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Human Genome Research Institute; UK Dementia Research Institute; Medical Research Council; Cardiff University; Lieber Institute for Brain Development; European Regional Development Fund; Broad Institute; University of Washington; University of Chicago; U.S. Department of Health and Human Services; National Institutes of Health; National Institute on Aging; Llywodraeth Cymru","keywords":"Genome-wide association study; Locus (genetics); Genetic association; Disease; Computational biology; Genetics; Biology; Gene; Medicine; Single-nucleotide polymorphism; Internal medicine; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001827055,0.0008890725,0.0007383842,0.003179261,0.0005269242,0.001261319,0.000842438,0.0007209576,0.05714468],"category_scores_gemma":[0.004226624,0.0006166382,0.0005478034,0.00320668,0.0001690869,0.0007363952,0.001696927,0.001004444,0.01738433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003682611,"about_ca_system_score_gemma":0.001214962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006874437,"about_ca_topic_score_gemma":0.01310765,"domain_scores_codex":[0.9995666,0.00009456623,0.00005151779,0.0001026243,0.0001457945,0.00003886312],"domain_scores_gemma":[0.9978402,0.001135253,0.0001588471,0.000270536,0.0003440702,0.0002510458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001079727,0.0001586271,0.02361344,0.001647107,0.0003102211,0.0009033629,0.0006376026,0.00133311,0.01097438,0.006374363,0.8788154,0.07415269],"study_design_scores_gemma":[0.0007336198,0.0001038757,0.04520136,0.0006243963,0.0002170134,0.001788486,0.0003980534,0.008615835,0.00832948,0.01477579,0.9190715,0.0001405958],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"software","genre_scores_codex":[0.0160493,0.001327242,0.03365629,0.001306499,0.000253419,0.0002912027,0.867904,0.06670688,0.0125052],"genre_scores_gemma":[0.05178538,0.001390266,0.08040844,0.001058605,0.000164624,0.00062712,0.8397966,0.01110389,0.01366507],"genre_candidate":"software","genre_consensus":null,"teacher_disagreement_score":0.05714468,"threshold_uncertainty_score":0.191168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01343121364297515,"score_gpt":0.2279029567100584,"score_spread":0.2144717430670832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}