{"id":"W3014348002","doi":"10.1016/j.eururo.2020.03.001","title":"The Oral Gonadotropin-releasing Hormone Receptor Antagonist Relugolix as Neoadjuvant/Adjuvant Androgen Deprivation Therapy to External Beam Radiotherapy in Patients with Localised Intermediate-risk Prostate Cancer: A Randomised, Open-label, Parallel-group Phase 2 Trial","year":2020,"lang":"en","type":"article","venue":"European Urology","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Myovant Sciences; National Institute for Health and Care Research; Cancer Research UK","keywords":"Medicine; Prostate cancer; Androgen deprivation therapy; Urology; External beam radiotherapy; Castration; Clinical endpoint; Goserelin; Radiation therapy; Internal medicine; Oncology; Randomized controlled trial; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002142145,0.001815606,0.002996445,0.0005089459,0.0003800619,0.001008915,0.001080049,0.001408653,0.004857307],"category_scores_gemma":[0.001488348,0.0007536357,0.001716115,0.0004227704,0.001387815,0.001001632,0.000447745,0.002862605,0.0008361274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007417949,"about_ca_system_score_gemma":0.001257941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007230231,"about_ca_topic_score_gemma":0.001952105,"domain_scores_codex":[0.999298,0.0003833612,0.00004252475,0.0001285608,0.00005054776,0.0000970898],"domain_scores_gemma":[0.9989496,0.000254708,0.0002857768,0.00009962921,0.00005565311,0.0003547137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9739798,0.01432234,0.0004764531,0.0002665041,0.0002926411,0.00002672838,0.00004183987,0.000214644,0.002624752,0.00003256082,0.0001952334,0.007526525],"study_design_scores_gemma":[0.8615956,0.1364105,0.001111561,0.00001271444,0.0001479183,0.00002239582,0.00001311177,0.0001751716,0.0002533679,0.00003471655,0.0002139073,0.00000899439],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938446,0.001795525,0.0002509553,0.0002486682,0.000239935,0.002544755,0.0003570013,0.00005364421,0.0006650556],"genre_scores_gemma":[0.9888348,0.001804396,0.001223495,0.0006109339,0.0004993264,0.004369055,0.0006610809,0.00001874975,0.001978269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004857307,"threshold_uncertainty_score":0.0162493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02050125745166244,"score_gpt":0.2917673092677259,"score_spread":0.2712660518160634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}