{"id":"W3014403732","doi":"10.1016/j.stem.2020.03.008","title":"Islet-Resident Endocrine Progenitors: A New Hope for Beta Cell PROCReation?","year":2020,"lang":"en","type":"letter","venue":"Cell stem cell","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Rehabilitation Institute; University of Toronto; University Health Network","funders":"","keywords":"Biology; Endocrine system; Islet; Progenitor cell; Beta cell; Pancreas; Enteroendocrine cell; Population; Progenitor; Cell; Cell biology; Endocrinology; Internal medicine; Stem cell; Diabetes mellitus; Genetics; Medicine; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00009908478,0.000800884,0.001251226,0.0002457144,0.0001508456,0.0001285445,0.0003378602,0.0005581634,0.00115283],"category_scores_gemma":[0.00002903623,0.000707095,0.0006114516,0.0003082466,0.00006358168,0.00009290386,0.0001111944,0.001116572,0.001511673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002281081,"about_ca_system_score_gemma":0.0008695669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008231725,"about_ca_topic_score_gemma":8.792038e-7,"domain_scores_codex":[0.9963433,0.00009347509,0.0008459706,0.001108823,0.0007407476,0.000867696],"domain_scores_gemma":[0.997524,0.0003729643,0.0004961204,0.0008228077,0.0002689717,0.000515184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001777101,0.0001460215,0.0002727229,0.005735369,0.0001075022,0.0003146487,0.0002443778,0.000001899769,0.01134349,0.000002058852,0.9811946,0.0004595755],"study_design_scores_gemma":[0.003606597,0.000712247,0.00000851094,0.0001840091,0.001019221,0.00001459073,0.0001105181,0.00005485859,0.2550437,0.00002505091,0.7387344,0.0004863231],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.0119216,0.01659438,0.001919607,0.7137886,0.004343181,0.01758696,0.0005141995,0.001354835,0.2319766],"genre_scores_gemma":[0.003747433,0.0002478804,0.002401206,0.3448506,0.01830031,0.0008095513,0.002678709,0.0003646057,0.6265997],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.394623,"threshold_uncertainty_score":0.9997603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02247246563635651,"score_gpt":0.241404481740447,"score_spread":0.2189320161040905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}