{"id":"W3014446514","doi":"","title":"Induction of an anti-angiogenesis factor, Thrombospondin 1 (TSP-1), by a novel histone deacetylase inhibitor, MGCD0103, in human cancer cells in vitro and in vivo","year":2008,"lang":"en","type":"article","venue":"Cancer Research","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Angiogenesis; Cancer research; Thrombospondin 1; Histone deacetylase inhibitor; Cancer; Peripheral blood mononuclear cell; Medicine; In vitro; Histone deacetylase; Biology; Internal medicine; Histone; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001267989,0.000288979,0.0002874772,0.0002372834,0.000126096,0.0001911027,0.0001359275,0.0001548205,0.0008031693],"category_scores_gemma":[0.00007440565,0.0001466312,0.0002552003,0.0001902846,0.0001490743,0.00005912509,0.00009570241,0.000453365,0.0001772656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003076553,"about_ca_system_score_gemma":0.000351578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002169068,"about_ca_topic_score_gemma":0.004106788,"domain_scores_codex":[0.9998989,0.00001688231,0.000007826869,0.0000220661,0.00002837223,0.00002586395],"domain_scores_gemma":[0.9999536,0.0000102048,0.000009890452,0.000005907582,0.000006201984,0.00001420703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003087025,0.0001334447,0.0003182688,0.00003511412,0.000009676432,0.00002682748,0.00002097326,0.0001262468,0.9960151,0.0000300598,0.0001208145,0.002854711],"study_design_scores_gemma":[0.0001082287,0.002187312,0.007797448,0.000003513861,0.00003075612,0.0002064536,0.00002146607,0.001197719,0.9859123,0.00001898354,0.002512779,0.000002987207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953603,0.001702705,0.001413659,0.00006887146,0.0000281491,0.00004661797,0.0004236902,0.0000699529,0.0008860155],"genre_scores_gemma":[0.9946064,0.001068474,0.001404737,0.0000589595,0.000009689221,0.00005374501,0.001298536,0.000009202917,0.001490192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002169068,"threshold_uncertainty_score":0.004312873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05304892397541062,"score_gpt":0.3840525661258173,"score_spread":0.3310036421504067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}