{"id":"W3014462878","doi":"10.4049/jimmunol.1901477","title":"Translating JAKs to Jakinibs","year":2020,"lang":"en","type":"review","venue":"The Journal of Immunology","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Identification (biology); Disease; Immune system; Biology; Computational biology; Medicine; Immunology; Bioinformatics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009441799,0.0006346548,0.0007698514,0.001250059,0.0002430622,0.001276822,0.0005453413,0.0009213156,0.005213405],"category_scores_gemma":[0.001208109,0.0002065711,0.0003837558,0.0006842607,0.0004517867,0.001534008,0.0007761284,0.003816676,0.003251842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006999266,"about_ca_system_score_gemma":0.0007739537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000443678,"about_ca_topic_score_gemma":0.001115357,"domain_scores_codex":[0.9997972,0.00004464832,0.00001931664,0.00002393586,0.00008638258,0.00002858531],"domain_scores_gemma":[0.9997166,0.0001321258,0.00002565012,0.000009962913,0.00007686672,0.00003887007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002207259,0.0001299456,0.00009431734,0.007358904,0.00008591697,0.0003255208,0.00008174224,0.0005978483,0.004064537,0.02376208,0.1130462,0.8502323],"study_design_scores_gemma":[0.00003661177,0.0001019234,0.00016195,0.001629446,0.00002916035,0.0003756035,0.00003064667,0.00009461785,0.0006467918,0.004500663,0.9923833,0.000009368007],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003895655,0.9904153,0.0003967524,0.002661186,0.002571519,0.00001349399,0.00005057166,0.00003699023,0.003464592],"genre_scores_gemma":[0.003281063,0.9887089,0.0004879791,0.002414961,0.001398493,0.00001890588,0.00008360365,0.000008768295,0.003597354],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005213405,"threshold_uncertainty_score":0.01744062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08061075874983195,"score_gpt":0.3744320534620271,"score_spread":0.2938212947121951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}