{"id":"W3014539959","doi":"10.1007/s00280-020-04063-7","title":"Docetaxel dose-intensity effect on overall survival in patients with metastatic castrate-sensitive prostate cancer","year":2020,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Docetaxel; Medicine; Prostate cancer; Internal medicine; Oncology; Univariate analysis; Proportional hazards model; Cancer; Discontinuation; Prostate-specific antigen; Chemotherapy; Retrospective cohort study; Urology; Multivariate analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000235295,0.0002194377,0.0003593942,0.000131584,0.0001153412,0.000254743,0.0001622617,0.0001602821,0.0009000779],"category_scores_gemma":[0.0007563388,0.00008888068,0.0004299616,0.0002020657,0.0001509282,0.0001559593,0.0001151527,0.0004707865,0.00008160932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003926863,"about_ca_system_score_gemma":0.0003352827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002454871,"about_ca_topic_score_gemma":0.00870856,"domain_scores_codex":[0.9999018,0.00003660731,0.000006021472,0.00001266669,0.00001538567,0.00002754422],"domain_scores_gemma":[0.999754,0.00007853124,0.00005766751,0.0000170393,0.00001125789,0.00008149907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.3247209,0.00536247,0.2970173,0.0006130824,0.002824228,0.000710125,0.0005201533,0.01261183,0.04192543,0.000690017,0.004035777,0.3089686],"study_design_scores_gemma":[0.003599619,0.05068194,0.9379723,0.00003868434,0.001024507,0.0004626077,0.00009735051,0.001725465,0.001586652,0.0002159245,0.002566847,0.00002806758],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995276,0.002965889,0.000068406,0.000111806,0.00002425875,0.00001317,0.0001774186,0.00001056093,0.001352548],"genre_scores_gemma":[0.9985169,0.0005716262,0.00004660774,0.00005683389,0.00002278562,0.000004731163,0.0001865268,0.00000241617,0.0005915869],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002454871,"threshold_uncertainty_score":0.004881203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02855337228452725,"score_gpt":0.3441792482954114,"score_spread":0.3156258760108841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}