{"id":"W3014578203","doi":"10.1177/0961203320917460","title":"Thrombotic microangiopathy in the course of catastrophic antiphospholipid syndrome successfully treated with eculizumab: case report and systematic review of the literature","year":2020,"lang":"en","type":"review","venue":"Lupus","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Eculizumab; Thrombotic microangiopathy; Medicine; Antiphospholipid syndrome; Catastrophic antiphospholipid syndrome; Atypical hemolytic uremic syndrome; Monoclonal; Internal medicine; Complement system; Intensive care medicine; Immunology; Monoclonal antibody; Antibody; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":{"n_in":0,"stratum":"aff_core","weight":5595.2375,"opus":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Case report plus systematic review of a drug's efficacy in a rare syndrome; clinical question."},"gpt":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"This systematic review evaluates a treatment for a clinical syndrome rather than evidence synthesis methodology."},"grok":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Clinical review of eculizumab in catastrophic antiphospholipid syndrome, not metaresearch."}}}