{"id":"W3015097837","doi":"10.1136/jitc-2019-000371","title":"Conditional immune toxicity rate in patients with metastatic renal and urothelial cancer treated with immune checkpoint inhibitors","year":2020,"lang":"en","type":"article","venue":"Journal for ImmunoTherapy of Cancer","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Common Terminology Criteria for Adverse Events; Adverse effect; Internal medicine; Incidence (geometry); Cumulative incidence; Renal cell carcinoma; Cancer; Cohort; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003524236,0.0003315464,0.0007893421,0.0001740827,0.0001410478,0.00004258695,0.0001185263,0.00007670338,0.0006051922],"category_scores_gemma":[0.00001904505,0.0002187736,0.0002202434,0.0003781436,0.0002769007,0.0002380764,0.00001258285,0.0003486701,4.391474e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002326182,"about_ca_system_score_gemma":0.0005009347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005347729,"about_ca_topic_score_gemma":0.00009728699,"domain_scores_codex":[0.9979678,0.0000766358,0.0008829102,0.000286845,0.0004347193,0.0003510481],"domain_scores_gemma":[0.9986021,0.00006583827,0.0006751286,0.0001503423,0.0003697506,0.0001368708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.2256406,0.0007690844,0.1412286,0.0003636901,0.004421304,0.00003014414,0.001734763,0.0003735618,0.5900525,0.00002102342,0.000439613,0.03492511],"study_design_scores_gemma":[0.07493095,0.008223968,0.6730513,0.001397827,0.0003868062,0.00003845761,0.0002301314,0.0001464609,0.2339544,0.00005925646,0.007063415,0.0005169931],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858917,0.009072083,0.0002629945,0.003225332,0.0001348565,0.00112873,0.0002416143,0.00001775195,0.00002492678],"genre_scores_gemma":[0.9951373,0.00244891,0.0005173732,0.001250458,0.0001880289,0.0001681122,0.00004530234,0.00007725312,0.0001672162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5318227,"threshold_uncertainty_score":0.8921329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01456777928565317,"score_gpt":0.2799380632421677,"score_spread":0.2653702839565145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}