{"id":"W3015243915","doi":"10.1111/bjd.19132","title":"Long-term efficacy and safety of brodalumab in psoriasis through 120 weeks and after withdrawal and retreatment: subgroup analysis of a randomized phase III trial (AMAGINE-1)","year":2020,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"Bausch Health; Ortho Dermatologics","keywords":"Medicine; Placebo; Psoriasis Area and Severity Index; Randomized controlled trial; Internal medicine; Psoriasis; Dermatology; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008292395,0.001749293,0.005901471,0.0006595245,0.0004509571,0.001702731,0.001028814,0.001766012,0.003248947],"category_scores_gemma":[0.00648046,0.0006731062,0.01191379,0.0006332482,0.0007148246,0.0008861519,0.0005996533,0.002340179,0.0003881403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008806713,"about_ca_system_score_gemma":0.001151851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007099363,"about_ca_topic_score_gemma":0.001946785,"domain_scores_codex":[0.9963325,0.002055085,0.0005145613,0.0005166034,0.0003125878,0.0002687917],"domain_scores_gemma":[0.9965115,0.001421174,0.0009616007,0.0005228262,0.0002202194,0.0003625834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9599409,0.0007265166,0.002689074,0.001160079,0.02352101,0.00004945599,0.00005155735,0.0002972846,0.001650574,0.00004944109,0.0003857917,0.009478323],"study_design_scores_gemma":[0.9036934,0.03625544,0.0174102,0.0002216261,0.039388,0.0001166741,0.00006926927,0.0009023816,0.0006690146,0.0003975281,0.0008185628,0.00005801358],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9514974,0.03831814,0.001888371,0.0008667725,0.0008864748,0.003375644,0.001652009,0.0001619215,0.001353226],"genre_scores_gemma":[0.987213,0.004745063,0.001292261,0.0007358355,0.0004405446,0.00319697,0.001263714,0.00004336983,0.001069246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008292395,"threshold_uncertainty_score":0.04385489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01067272546066037,"score_gpt":0.2536275253746416,"score_spread":0.2429547999139813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}