{"id":"W3015339288","doi":"10.1101/2020.04.09.034165","title":"Friend or foe? Effects of host immune activation on the transient gut microbiome in the caterpillar <i>Manduca sexta</i>","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Viral Infections and Vectors","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Manduca sexta; Immune system; Biology; Microbiome; Immunology; Immunity; Gut flora; Gut bacteria; Manduca; Bacteria; Innate immune system; Host (biology); Hemolymph; Microbiology; Insect; Ecology; Bioinformatics; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001901288,0.000233209,0.0003280475,0.0002656808,0.0004156601,0.0005675196,0.0001748095,0.0004190029,0.001742433],"category_scores_gemma":[0.0002314661,0.0001526213,0.0002689673,0.00008565714,0.0004125917,0.000250693,0.0003291405,0.0007053609,0.0002671334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003488942,"about_ca_system_score_gemma":0.0001199195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008095229,"about_ca_topic_score_gemma":0.002217567,"domain_scores_codex":[0.9998426,0.00003050525,0.00000582359,0.00005184998,0.00002398089,0.00004522099],"domain_scores_gemma":[0.9996659,0.0000685868,0.00009618716,0.00002194936,0.00002749492,0.0001199693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005870683,0.00004901681,0.006981905,0.00004911905,0.00002151648,0.0001356698,0.0001112351,0.00002127373,0.9898809,0.00004464103,0.0001184488,0.001999201],"study_design_scores_gemma":[0.00003016106,0.002903607,0.6890526,0.00003886421,0.00009922185,0.0006803779,0.001314208,0.001224591,0.3014154,0.0002945743,0.00290223,0.00004426739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984958,0.0005096042,0.000186042,0.0002079726,0.00001626667,0.000004884847,0.00007957035,0.00002326225,0.0004766028],"genre_scores_gemma":[0.9987286,0.00009873517,0.0002529574,0.0001660315,0.00001138086,0.000008569581,0.0000686537,0.000006393382,0.0006585745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001742433,"threshold_uncertainty_score":0.005828977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01836250956538332,"score_gpt":0.2358206503979199,"score_spread":0.2174581408325366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}