{"id":"W3015373377","doi":"10.1128/mcb.00191-19","title":"Nocodazole-Induced Expression and Phosphorylation of Anillin and Other Mitotic Proteins Are Decreased in DNA-Dependent Protein Kinase Catalytic Subunit-Deficient Cells and Rescued by Inhibition of the Anaphase-Promoting Complex/Cyclosome with proTAME but Not Apcin","year":2020,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences; Cumming School of Medicine, University of Calgary; National Cancer Institute; Government of Canada; National Institutes of Health; Canadian Institutes of Health Research; Alberta Cancer Foundation; Cancer Research Society","keywords":"Securin; Biology; Nocodazole; Cell biology; PLK1; Phosphorylation; Molecular biology; Anaphase-promoting complex; Cyclin B1; Cyclin-dependent kinase 1; Cell cycle; Anaphase; Biochemistry; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008216835,0.000650601,0.0002774654,0.0002837592,0.0001446422,0.000247401,0.0002477111,0.0002691195,0.001578544],"category_scores_gemma":[0.00006572899,0.0001805088,0.0002478969,0.0001539389,0.0002072526,0.0001621559,0.0001797671,0.0006445051,0.0003928205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000271494,"about_ca_system_score_gemma":0.0002155072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007213995,"about_ca_topic_score_gemma":0.001169649,"domain_scores_codex":[0.9998641,0.00001193081,0.00002546208,0.00003268779,0.00003440712,0.000031294],"domain_scores_gemma":[0.9998863,0.000009599826,0.00003615902,0.00001440607,0.00000842498,0.00004512749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006277877,0.00001406871,0.00005040444,0.00002699208,0.000003279956,0.00003059858,0.00000368763,0.00001663162,0.9994444,0.00003619367,0.00002194286,0.0002888955],"study_design_scores_gemma":[0.00001989024,0.0001114516,0.003891933,0.000005362205,0.000008935582,0.0001599106,0.00001361364,0.0003332665,0.9935378,0.00002529874,0.001889319,0.000003161198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919223,0.002697795,0.001848647,0.0001443508,0.00008678092,0.00003802721,0.00124215,0.0002042165,0.001815842],"genre_scores_gemma":[0.9891412,0.001375861,0.001728713,0.00005634816,0.00001180048,0.00008308664,0.001610326,0.00003388638,0.005958876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001578544,"threshold_uncertainty_score":0.005280733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009958650061668272,"score_gpt":0.204057352034051,"score_spread":0.1940987019723827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}