{"id":"W3015478652","doi":"10.1016/j.bmc.2020.115494","title":"Inhibition of bacterial growth and galactosyltransferase activity of WbwC by α, ω-bis(3-alkyl-1H-imidazolium)alkane salts: Effect of varying carbon content","year":2020,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Glycomics Network; Canadian Institutes of Health Research","keywords":"Chemistry; Alkyl; Antimicrobial; Antiseptic; Bacteria; Organic chemistry; Alkane; Enzyme; Bacterial growth; Stereochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001584001,0.0004681768,0.0002471683,0.0001481201,0.00009785872,0.0001688191,0.0002673184,0.0003051484,0.001204285],"category_scores_gemma":[0.0002664494,0.0001560698,0.000164201,0.0003228,0.000157965,0.0001982012,0.0001275469,0.000504309,0.0003919777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001779104,"about_ca_system_score_gemma":0.000227452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001210783,"about_ca_topic_score_gemma":0.001374969,"domain_scores_codex":[0.999858,0.0000251721,0.00002539401,0.00002154873,0.00003124258,0.00003860221],"domain_scores_gemma":[0.9997595,0.00006779357,0.00004870932,0.00002337221,0.00003221431,0.00006837058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004347172,0.00003752204,0.00006995008,0.00002072433,0.000002701463,0.00002168792,0.000008364893,0.00004959262,0.9987994,0.00002074244,0.00002106099,0.0005133573],"study_design_scores_gemma":[0.00001113051,0.0003371291,0.0007867634,0.000002367811,0.000004388077,0.00001889867,0.000005822984,0.0002010227,0.9984391,0.000005313155,0.0001857001,0.000002341913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975849,0.0006153234,0.0005096467,0.00005008227,0.00002921069,0.000012235,0.0003124323,0.00004604098,0.0008400698],"genre_scores_gemma":[0.9953173,0.0005316148,0.0013158,0.00003088157,0.00001081137,0.00002224393,0.0009342078,0.0000229313,0.001814268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001210783,"threshold_uncertainty_score":0.004028738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286384592561057,"score_gpt":0.2108351394569271,"score_spread":0.1979712935313165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}