{"id":"W3015518897","doi":"10.3390/cells9040906","title":"A Commercial Probiotic Induces Tolerogenic and Reduces Pathogenic Responses in Experimental Autoimmune Encephalomyelitis","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Instituto de Salud Carlos III; Agència de Gestió d'Ajuts Universitaris i de Recerca","keywords":"Experimental autoimmune encephalomyelitis; Multiple sclerosis; Probiotic; Immunology; Immune system; Microbiome; Encephalomyelitis; Inflammation; Disease; Medicine; Autoimmune disease; Biology; Bioinformatics; Bacteria; Antibody; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009462819,0.0001374861,0.0001664454,0.00003075142,0.000063701,0.00002475839,0.0001298284,0.0001265617,0.00003505042],"category_scores_gemma":[0.00002017778,0.0001395202,0.00004537352,0.00008709,0.00009637565,0.000004582068,0.0001243675,0.0001066559,0.00001678118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001396057,"about_ca_system_score_gemma":0.0001193683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002898583,"about_ca_topic_score_gemma":0.00001063254,"domain_scores_codex":[0.9990507,0.0001048885,0.0002102653,0.0003380381,0.00005239293,0.0002437099],"domain_scores_gemma":[0.9996918,0.0000100928,0.00005130501,0.0001291514,0.00001500673,0.0001026388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001348426,0.00005101509,0.0002772162,0.0000209293,0.000008959851,0.000009327566,0.001100109,0.000001382431,0.9966444,0.00000668763,0.0003567832,0.001388306],"study_design_scores_gemma":[0.0006083975,0.0003957605,0.02689203,0.0000202402,0.000005780798,0.00001621276,0.0005671054,0.000006528902,0.9678147,0.000002998448,0.003498902,0.0001713189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930888,0.00588806,0.000002701084,0.0005451927,0.00009551416,0.0002434724,0.00002044986,0.00001148177,0.0001042835],"genre_scores_gemma":[0.9984118,0.0003243788,0.0002250822,0.0007558619,0.0001224155,0.00001090123,0.00003430895,0.00001585427,0.00009942572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02882972,"threshold_uncertainty_score":0.5689468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02128964177910323,"score_gpt":0.2677013592583012,"score_spread":0.246411717479198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}