{"id":"W3015518897","doi":"10.3390/cells9040906","title":"A Commercial Probiotic Induces Tolerogenic and Reduces Pathogenic Responses in Experimental Autoimmune Encephalomyelitis","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Instituto de Salud Carlos III; Agència de Gestió d'Ajuts Universitaris i de Recerca","keywords":"Experimental autoimmune encephalomyelitis; Multiple sclerosis; Probiotic; Immunology; Immune system; Microbiome; Encephalomyelitis; Inflammation; Disease; Medicine; Autoimmune disease; Biology; Bioinformatics; Bacteria; Antibody; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002511327,0.0004484616,0.0005026811,0.0003589686,0.0001657022,0.0002788901,0.0001729161,0.000386696,0.001379612],"category_scores_gemma":[0.000203434,0.0001172306,0.0002064175,0.0002394034,0.0002392537,0.0002357653,0.0002793529,0.0007054355,0.0001939278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001286895,"about_ca_system_score_gemma":0.0001866129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002163455,"about_ca_topic_score_gemma":0.000565549,"domain_scores_codex":[0.9997981,0.00004495076,0.00002192732,0.00003376495,0.00005658234,0.00004468534],"domain_scores_gemma":[0.9998437,0.00002046587,0.00004342126,0.00001364334,0.00001451894,0.00006422114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001442029,0.0007569965,0.0002419686,0.00008864905,0.00001130002,0.00002654799,0.00001570271,0.00002926398,0.9935423,0.0000191244,0.00002704569,0.003799079],"study_design_scores_gemma":[0.0003789526,0.03126816,0.01698361,0.00005003532,0.00009685734,0.0003074004,0.00008211158,0.0004340593,0.948094,0.00007751107,0.002215951,0.00001136695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973442,0.001355309,0.0004920498,0.00007885413,0.00003761987,0.00002884016,0.00009424148,0.00003788792,0.0005310594],"genre_scores_gemma":[0.9955804,0.001193923,0.001649508,0.00009005552,0.00003574169,0.00005548969,0.0002718378,0.00001905349,0.00110395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001379612,"threshold_uncertainty_score":0.004615247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02128964177910323,"score_gpt":0.2677013592583012,"score_spread":0.246411717479198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}