{"id":"W3015623467","doi":"10.1111/sji.12888","title":"On T cell development, T cell signals, T cell specificity and sensitivity, and the autoimmunity facilitated by lymphopenia","year":2020,"lang":"en","type":"article","venue":"Scandinavian Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Medical Association; Women and Children’s Health Research Institute; University of Alberta; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"T-cell receptor; T cell; Cell biology; Antigen; MHC restriction; Biology; Major histocompatibility complex; Autoimmunity; Cytotoxic T cell; Cell growth; Receptor; Immunology; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000713093,0.0007368863,0.0007344466,0.001112989,0.000573398,0.001615352,0.0006515603,0.001322214,0.003335437],"category_scores_gemma":[0.0003731603,0.0002368689,0.0002724755,0.0006349407,0.003499068,0.002161184,0.001027242,0.001261269,0.00056657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007348277,"about_ca_system_score_gemma":0.0006114985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009393109,"about_ca_topic_score_gemma":0.001670222,"domain_scores_codex":[0.9995891,0.0001417088,0.00003188151,0.0000644157,0.00008385494,0.00008886595],"domain_scores_gemma":[0.9996978,0.000147369,0.00006089817,0.00001988522,0.00003122863,0.00004289808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007737289,0.0001638796,0.005869085,0.002639596,0.00007589928,0.0100281,0.001887104,0.00827188,0.1314735,0.6779681,0.009983397,0.1508657],"study_design_scores_gemma":[0.00009017323,0.00152153,0.02306289,0.00176548,0.0001430899,0.007135971,0.001992266,0.01211068,0.03320579,0.7013249,0.2174685,0.0001785513],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2811942,0.4277798,0.07392499,0.0422705,0.003331414,0.0001181636,0.0004141905,0.0004930478,0.1704737],"genre_scores_gemma":[0.8134534,0.1388755,0.01076015,0.005417832,0.002500198,0.0001280599,0.0001280176,0.00008247784,0.0286544],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003335437,"threshold_uncertainty_score":0.01115817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092714145794177,"score_gpt":0.1959466169410933,"score_spread":0.1850194754831516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}