{"id":"W3015623467","doi":"10.1111/sji.12888","title":"On T cell development, T cell signals, T cell specificity and sensitivity, and the autoimmunity facilitated by lymphopenia","year":2020,"lang":"en","type":"article","venue":"Scandinavian Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Medical Association; Women and Children’s Health Research Institute; University of Alberta; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"T-cell receptor; T cell; Cell biology; Antigen; MHC restriction; Biology; Major histocompatibility complex; Autoimmunity; Cytotoxic T cell; Cell growth; Receptor; Immunology; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001075483,0.00050282,0.001066845,0.0001871498,0.0006825578,0.00006309095,0.0004485367,0.0004987507,0.0003950976],"category_scores_gemma":[0.0001279025,0.0003561827,0.0001727348,0.0002455637,0.001937974,0.0001651821,0.0003959002,0.001505573,0.0002746731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008854627,"about_ca_system_score_gemma":0.0001870805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001149192,"about_ca_topic_score_gemma":0.000007906353,"domain_scores_codex":[0.9959231,0.001851662,0.0009820748,0.0004561661,0.00009657595,0.0006904458],"domain_scores_gemma":[0.9975222,0.001035222,0.0008145589,0.0003338078,0.000192908,0.000101351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003360088,0.0003230416,0.000860791,0.00004426524,0.000284233,0.000098444,0.003372734,0.000006167279,0.9842788,0.0001054817,0.005118003,0.002147963],"study_design_scores_gemma":[0.01691968,0.001963866,0.002093458,0.00005954777,0.0001524601,0.00115208,0.002346344,0.00001036651,0.9432101,0.0002420394,0.03131567,0.0005344302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9638527,0.03141776,0.000258742,0.001855553,0.0005961222,0.0003194475,0.00005436182,0.00003993714,0.001605358],"genre_scores_gemma":[0.9958418,0.001391606,0.00010091,0.0008000417,0.00002778988,0.000005162521,0.0000402303,0.00003426848,0.001758183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04106872,"threshold_uncertainty_score":0.999889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092714145794177,"score_gpt":0.1959466169410933,"score_spread":0.1850194754831516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}