{"id":"W3015761749","doi":"10.1038/s41467-020-15609-x","title":"RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute of General Medical Sciences; U.S. Department of Health and Human Services; National Institutes of Health; Compute Canada; National Heart, Lung, and Blood Institute; McGill University; Canadian Institutes of Health Research; David and Lucile Packard Foundation","keywords":"PRC2; Chromatin; RNA; DNA; Biology; Cell biology; Genetics; Molecular biology; Gene; Histone H3","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001206974,0.0003285401,0.000128181,0.0001476438,0.0001851306,0.0003413822,0.0002038405,0.0001819852,0.001748933],"category_scores_gemma":[0.0001652043,0.0001953382,0.0002006821,0.00007741746,0.0001510293,0.0002553492,0.0002611545,0.0002829919,0.0008280227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003059685,"about_ca_system_score_gemma":0.000152254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006037594,"about_ca_topic_score_gemma":0.001499154,"domain_scores_codex":[0.9998602,0.00002281514,0.000007380282,0.00004645924,0.00004223298,0.00002095748],"domain_scores_gemma":[0.9999461,0.000008973553,0.00001523171,0.000009618911,0.000006055763,0.00001397191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004007724,0.000004531917,0.0003853505,0.00001684107,0.000004938466,0.00004976115,0.00001217527,0.00007118587,0.9971408,0.000237089,0.00007134028,0.001965962],"study_design_scores_gemma":[0.00001120385,0.00005659641,0.006885165,0.000003361883,0.000005946701,0.0002591618,0.00001997731,0.001887039,0.9862884,0.0001271069,0.004450434,0.000005490083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977038,0.003072031,0.0106173,0.0002421647,0.00004569024,0.00002999716,0.0002461873,0.0003646638,0.008344111],"genre_scores_gemma":[0.991881,0.0003695966,0.002006198,0.00004333487,0.0000106856,0.000011395,0.0002785815,0.0000224524,0.005376784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001748933,"threshold_uncertainty_score":0.005850732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03756009082902366,"score_gpt":0.3059189542512922,"score_spread":0.2683588634222686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}