{"id":"W3015850611","doi":"10.1016/j.tree.2020.03.002","title":"A Roadmap for Understanding the Evolutionary Significance of Structural Genomic Variation","year":2020,"lang":"en","type":"review","venue":"Trends in Ecology & Evolution","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":385,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Marsden Fund; James S. McDonnell Foundation; Vetenskapsrådet; National Institutes of Health; Fonds de Recherche du Québec - Santé; Banting Research Foundation","keywords":"Variation (astronomy); Structural variation; Evolutionary biology; Computational biology; Biology; Genetics; Genome; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002052902,0.0002525445,0.0006426415,0.0001360269,0.0001281288,0.00000565706,0.0002670227,0.0003375897,0.000009409488],"category_scores_gemma":[0.00006818569,0.0002041181,0.0002954222,0.0002181022,0.0001500263,0.000001083731,0.0001243991,0.0001405766,0.00000161908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000389127,"about_ca_system_score_gemma":0.0002606775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001936292,"about_ca_topic_score_gemma":0.000200153,"domain_scores_codex":[0.9985592,0.0001792008,0.0005111399,0.0004305726,0.00006504927,0.0002548196],"domain_scores_gemma":[0.9991549,0.00009896439,0.0004242621,0.0002518673,0.00004237375,0.00002763005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009520274,0.0003659211,0.01270011,0.009218774,0.005210791,0.000007908012,0.00167008,0.006705591,0.01452154,0.04059324,0.0115785,0.8964755],"study_design_scores_gemma":[0.001975348,0.00164509,0.1542331,0.0004835545,0.001827705,0.00007220433,0.000381312,0.002289939,0.00002068362,0.01762828,0.8181695,0.001273259],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00142959,0.9944918,0.002450139,0.0001177437,0.0005175415,0.0006575756,0.000222782,0.000003696856,0.0001091484],"genre_scores_gemma":[0.355613,0.6425064,0.000613827,0.00001856064,0.0003936558,0.0003173571,0.0003675766,0.00003615074,0.0001334984],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8952023,"threshold_uncertainty_score":0.8323693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04870773357187656,"score_gpt":0.3088036629570593,"score_spread":0.2600959293851827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}