{"id":"W3015928687","doi":"10.1021/acs.orglett.0c00900","title":"Intramolecular Palladium-Catalyzed Ring Opening of Oxabenzonorbornadienes with C<sub>1</sub>-Tethered Aryl Halides","year":2020,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic Cross-Coupling Reactions","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Chemistry; Intramolecular force; Aryl; Palladium; Substituent; Selectivity; Naphthalene; Catalysis; Halide; Ring (chemistry); Yield (engineering); Medicinal chemistry; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008956093,0.000291655,0.0003817629,0.00005231987,0.0001283605,0.0001096855,0.0004068897,0.00009878483,0.0003064637],"category_scores_gemma":[0.0001638345,0.0002900388,0.000112345,0.0003542719,0.000190729,0.0001706719,0.0001257043,0.0003331902,0.00005889282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001429242,"about_ca_system_score_gemma":0.0001016453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001058479,"about_ca_topic_score_gemma":0.00005741579,"domain_scores_codex":[0.9984112,0.000001876234,0.0003864871,0.0005076841,0.00028933,0.0004033842],"domain_scores_gemma":[0.998872,0.0001076684,0.0002384083,0.0005144278,0.00006415375,0.0002033182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000648036,0.00003066837,0.001560849,0.0001602344,0.0002034622,0.00009681718,0.0009753174,0.0002802275,0.9961717,0.00002130803,0.0001002938,0.0003342796],"study_design_scores_gemma":[0.0009732324,0.0000167994,0.0003411213,0.0001222473,0.000128612,0.00005860166,0.0003294512,0.0003732964,0.9972164,0.000006320772,0.0001028939,0.0003310091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967122,0.0000771214,0.0007832341,0.001971239,0.00005665912,0.000104421,0.00001844243,0.0001809952,0.000095709],"genre_scores_gemma":[0.9988866,0.00001131871,0.0001721343,0.000576924,0.0001669711,0.0000117679,0.0000611326,0.0001084399,0.000004668503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002174464,"threshold_uncertainty_score":0.9999552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01012527709765811,"score_gpt":0.2034401346195746,"score_spread":0.1933148575219165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}